HESI A2
Biology HESI A2 Practice Test
1. Which two bases are purines?
- A. Adenine (A)
- B. Cytosine (C)
- C. Thymine (T)
- D. Guanine (G)
Correct answer: A
Rationale: Adenine (A) and guanine (G) are the two bases that are purines. Purines are characterized by a double-ring structure containing two carbon rings, distinguishing them from pyrimidines. Adenine and guanine are purines because they possess this unique double-ring structure. Therefore, choices A and D, adenine and guanine, respectively, are the correct answers. Choices B and C, cytosine and thymine, are pyrimidines and do not exhibit the double-ring structure characteristic of purines.
2. Which cell organelle functions to transport materials from the endoplasmic reticulum throughout the cell?
- A. Ribosome
- B. Golgi apparatus
- C. Lysosome
- D. Vacuole
Correct answer: B
Rationale: The Golgi apparatus is the correct answer because it functions to transport materials from the endoplasmic reticulum throughout the cell. Ribosomes are responsible for protein synthesis, not transportation of materials. Lysosomes contain enzymes for digestion and waste removal, not for transporting materials. Vacuoles are primarily involved in storage, waste disposal, and maintaining turgor pressure, not in transporting materials from the endoplasmic reticulum.
3. The difference between diploid and haploid is as follows:
- A. Diploid organisms are multicellular
- B. Diploid cells are somatic
- C. Diploid cells have two sets of homologous chromosomes
- D. More than one of the above is true
Correct answer: D
Rationale: Option B correctly states that diploid cells are somatic cells that make up the body tissues and organs in an organism, while haploid cells are gametes involved in sexual reproduction. Option C accurately differentiates diploid and haploid cells based on their chromosome sets – diploid cells have two sets of homologous chromosomes (one from each parent), whereas haploid cells have one set of unpaired chromosomes. Therefore, the correct choice is D, as both statements in options B and C are accurate descriptions of the differences between diploid and haploid cells. Option A is incorrect because diploid and haploid refer to the number of sets of chromosomes in a cell, not whether the organism is multicellular or not.
4. During which phase of mitosis do the chromosomes align in the center of the cell?
- A. Prophase
- B. Metaphase
- C. Telophase
- D. Anaphase
Correct answer: B
Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.
5. Which of the following is necessary for cell diffusion?
- A. water
- B. membrane
- C. ATP
- D. gradient
Correct answer: D
Rationale: The correct answer is 'gradient.' In cell diffusion, substances move from an area of high concentration to an area of low concentration, driven by the concentration gradient. This process does not require water, membrane, or ATP specifically. Water can aid in the movement of substances, but it is not necessary for diffusion itself. The membrane is involved in regulating diffusion but is not a requirement for the process. ATP is not directly involved in simple diffusion processes; instead, it is more related to active transport mechanisms. Therefore, the concentration gradient is essential for cell diffusion to occur.
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