HESI A2
HESI A2 Anatomy and Physiology Practice Test 2023
1. Which vitamin is essential for the synthesis of collagen?
- A. Vitamin C
- B. Vitamin D
- C. Vitamin B12
- D. Vitamin K
Correct answer: A
Rationale: The correct answer is Vitamin C. Vitamin C is essential for the synthesis of collagen, a protein crucial for maintaining the structure and integrity of skin, blood vessels, and bones. It plays a key role in the hydroxylation of proline and lysine residues in collagen synthesis, which is necessary for the stability and strength of collagen fibers. Choice B: Vitamin D is essential for bone health and calcium absorption but is not directly involved in collagen synthesis. Choice C: Vitamin B12 is important for red blood cell formation and neurological function but is not directly related to collagen synthesis. Choice D: Vitamin K is necessary for blood clotting and bone metabolism but does not play a direct role in collagen synthesis.
2. Which of the following is an organ of the respiratory system?
- A. Brain
- B. Larynx
- C. Urethra
- D. Pancreas
Correct answer: B
Rationale: The larynx is an essential organ of the respiratory system. It plays a crucial role in producing sound, protecting the trachea from food aspiration, and regulating the airflow to and from the lungs. The brain is part of the nervous system, the urethra is part of the urinary system, and the pancreas is part of the digestive system. Therefore, they are not directly related to the respiratory system's functions.
3. Which organ in the body is responsible for insulin production?
- A. Pancreas
- B. Liver
- C. Gallbladder
- D. Kidneys
Correct answer: A
Rationale: The correct answer is the pancreas. The pancreas is responsible for producing insulin, a hormone crucial for regulating blood glucose levels. Insulin plays a key role in allowing cells to take in glucose, thereby helping to keep blood sugar levels in check. The liver (choice B), gallbladder (choice C), and kidneys (choice D) do not produce insulin. The liver is involved in glycogen storage and glucose regulation, the gallbladder stores bile, and the kidneys filter blood and regulate fluid balance.
4. Which hormone is responsible for regulating the sleep-wake cycle?
- A. Melatonin
- B. Thyroxine
- C. Insulin
- D. Cortisol
Correct answer: A
Rationale: Melatonin, produced by the pineal gland, regulates the sleep-wake cycle by responding to light and darkness in the environment. It plays a crucial role in signaling the body when it's time to sleep and wake up, helping to establish and maintain a healthy circadian rhythm. Thyroxine, Insulin, and Cortisol do not directly regulate the sleep-wake cycle, making them incorrect choices for this question.
5. When are gallstones most problematic?
- A. When they block a duct
- B. When they contain cholesterol
- C. When they contain bilirubin
- D. When they begin to dissolve
Correct answer: A
Rationale: Gallstones become most problematic when they block a duct, such as the bile duct or cystic duct. This blockage can lead to various complications, including inflammation, infection, and even damage to the gallbladder or liver. In severe cases, a blocked duct can cause intense pain, jaundice, and other serious symptoms that require medical intervention. Choices B, C, and D are incorrect because the presence of cholesterol or bilirubin in gallstones or the process of dissolution do not necessarily indicate when gallstones become most problematic. The critical issue arises when the stones obstruct a duct, leading to complications.
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