which vitamin is essential for the synthesis of collagen
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HESI A2

HESI A2 Anatomy and Physiology Practice Test 2023

1. Which vitamin is essential for the synthesis of collagen?

Correct answer: A

Rationale: The correct answer is Vitamin C. Vitamin C is essential for the synthesis of collagen, a protein crucial for maintaining the structure and integrity of skin, blood vessels, and bones. It plays a key role in the hydroxylation of proline and lysine residues in collagen synthesis, which is necessary for the stability and strength of collagen fibers. Choice B: Vitamin D is essential for bone health and calcium absorption but is not directly involved in collagen synthesis. Choice C: Vitamin B12 is important for red blood cell formation and neurological function but is not directly related to collagen synthesis. Choice D: Vitamin K is necessary for blood clotting and bone metabolism but does not play a direct role in collagen synthesis.

2. Enlargement of the thyroid, commonly known as a goiter, might be expected to affect ___________.

Correct answer: A

Rationale: Enlargement of the thyroid, known as a goiter, can compress the nearby structures in the neck, including the esophagus. This compression can lead to symptoms such as difficulty swallowing (dysphagia) or a sensation of pressure in the throat. Therefore, an enlarged thyroid gland is expected to affect swallowing. Choices B, C, and D are incorrect because a goiter primarily affects structures in the neck due to its physical enlargement, rather than directly impacting insulin levels, sleep, or digestion.

3. When the pulmonary valve and aortic valves are open, where can blood flow?

Correct answer: C

Rationale: When the pulmonary valve and aortic valves are open, blood can flow between the heart and the rest of the body. The pulmonary valve allows blood to flow from the right ventricle to the lungs for oxygenation, while the aortic valve permits blood to flow from the left ventricle to the rest of the body for distribution of oxygen and nutrients. This circulation pathway ensures that oxygen-rich blood is pumped to the body tissues. Choices A, B, and D are incorrect because when the pulmonary valve and aortic valves are open, blood is not flowing between the ventricles, from atrium to ventricle, or between the atria; instead, it is being pumped out of the heart to the lungs and the rest of the body.

4. Which type of muscle tissue is found in the walls of hollow organs?

Correct answer: C

Rationale: Smooth muscle tissue is found in the walls of hollow organs such as the intestines, blood vessels, and bladder. It contracts involuntarily, allowing for functions like peristalsis in the intestines and regulation of blood flow in blood vessels. Skeletal muscle (Choice A) is attached to bones, cardiac muscle (Choice B) is found in the heart, and striated muscle (Choice D) refers to both skeletal and cardiac muscles due to their striped appearance, but neither of these types are typically found in the walls of hollow organs.

5. What is the role of the spleen in the lymphatic system?

Correct answer: A

Rationale: The spleen plays a crucial role in the lymphatic system by filtering blood, specifically removing old or damaged red blood cells. Additionally, the spleen produces lymphocytes, a type of white blood cell that plays a key role in the immune response by helping to fight off infections. Therefore, the correct answer is A, as the spleen is primarily involved in blood filtration and the production of lymphocytes rather than storing vitamins or regulating body temperature.

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