HESI A2
HESI A2 Anatomy and Physiology Practice Test 2023
1. Which vitamin is essential for the synthesis of collagen?
- A. Vitamin C
- B. Vitamin D
- C. Vitamin B12
- D. Vitamin K
Correct answer: A
Rationale: The correct answer is Vitamin C. Vitamin C is essential for the synthesis of collagen, a protein crucial for maintaining the structure and integrity of skin, blood vessels, and bones. It plays a key role in the hydroxylation of proline and lysine residues in collagen synthesis, which is necessary for the stability and strength of collagen fibers. Choice B: Vitamin D is essential for bone health and calcium absorption but is not directly involved in collagen synthesis. Choice C: Vitamin B12 is important for red blood cell formation and neurological function but is not directly related to collagen synthesis. Choice D: Vitamin K is necessary for blood clotting and bone metabolism but does not play a direct role in collagen synthesis.
2. Which gland produces hormones that regulate sleep?
- A. Thyroid gland
- B. Pineal gland
- C. Adrenal gland
- D. Pituitary gland
Correct answer: B
Rationale: The pineal gland secretes melatonin, a hormone that plays a crucial role in regulating the sleep-wake cycle. Melatonin production is influenced by exposure to light, with levels increasing in the evening to promote sleep and decreasing in the morning to signal wakefulness. Choices A, C, and D are incorrect because the thyroid gland primarily regulates metabolism, the adrenal gland produces hormones like adrenaline and cortisol related to stress response, and the pituitary gland controls various functions by releasing different hormones but not specifically related to regulating sleep.
3. What is the role of platelets in the blood?
- A. To transport oxygen
- B. To fight infections
- C. To clot blood
- D. To carry nutrients
Correct answer: C
Rationale: Platelets, also known as thrombocytes, play a crucial role in blood clotting. When there is an injury, platelets adhere to the site and release substances that form a clot, preventing excessive bleeding. This function is vital for maintaining hemostasis and preventing blood loss. Choice A is incorrect because red blood cells, not platelets, are responsible for transporting oxygen. Choice B is incorrect as white blood cells are primarily responsible for fighting infections. Choice D is incorrect as nutrients are mainly transported by plasma and red blood cells, not platelets.
4. Where are B-lymphocytes produced?
- A. Thymus
- B. Red bone marrow
- C. Lymph nodes
- D. Spleen
Correct answer: B
Rationale: B-lymphocytes are produced in the red bone marrow. The red bone marrow is the primary site for B-cell development, where they mature before entering the circulation. The thymus is responsible for T-lymphocyte maturation, not B-lymphocytes. Lymph nodes and spleen play roles in immune responses but are not the primary sites for B-lymphocyte production.
5. Which of the following structures regulates the transport of substances in and out of a cell?
- A. Nucleus
- B. Cell membrane
- C. Cytoplasm
- D. Mitochondria
Correct answer: B
Rationale: The cell membrane, also known as the plasma membrane, is responsible for regulating the transport of substances in and out of the cell. It acts as a selective barrier, allowing the passage of certain molecules while restricting others. This selective permeability helps maintain homeostasis within the cell by controlling the movement of essential substances like nutrients and waste products. The nucleus (Choice A) is the organelle that houses the cell's genetic material and is not directly involved in regulating substance transport. Cytoplasm (Choice C) is the gel-like substance that fills the cell and does not play a direct role in regulating substance transport. Mitochondria (Choice D) are responsible for energy production in the cell through cellular respiration and are not primarily involved in substance transport.
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