HESI A2
HESI A2 Practice Test Biology
1. Which of the following is necessary for cell diffusion?
- A. water
- B. membrane
- C. ATP
- D. gradient
Correct answer: D
Rationale: The correct answer is 'gradient.' In cell diffusion, substances move from an area of high concentration to an area of low concentration, driven by the concentration gradient. This process does not require water, membrane, or ATP specifically. Water can aid in the movement of substances, but it is not necessary for diffusion itself. The membrane is involved in regulating diffusion but is not a requirement for the process. ATP is not directly involved in simple diffusion processes; instead, it is more related to active transport mechanisms. Therefore, the concentration gradient is essential for cell diffusion to occur.
2. Which part of cellular respiration produces the greatest amount of ATP?
- A. electron transport chain
- B. glycolysis
- C. citric acid cycle
- D. fermentation
Correct answer: A
Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.
3. Which, if any, of the following statements are true?
- A. Water boils at approximately 100°C (212°F) at standard atmospheric pressure
- B. The boiling point is the temperature at which the vapor pressure is higher than the atmospheric pressure around the water
- C. Water boils at a lower temperature in areas of lower pressure
- D. A and C are true
Correct answer: D
Rationale: Both statements A and C are true. Water indeed boils at approximately 100°C (212°F) at standard atmospheric pressure. However, water boils at a lower temperature in areas of lower pressure due to the decreased atmospheric pressure, which affects the vapor pressure and boiling point of water. Statement B is incorrect because the boiling point is the temperature at which the vapor pressure equals the external pressure (atmospheric pressure in this case), not when it is higher.
4. Which animal has an open transport system?
- A. Grasshopper
- B. Earthworm
- C. Dolphin
- D. Chicken
Correct answer: B
Rationale: The correct answer is B: Earthworm. Earthworms have an open circulatory system, meaning their blood and interstitial fluid are not enclosed in blood vessels. Instead, the blood flows freely within the body cavity, allowing for direct exchange of nutrients and waste products with surrounding tissues. This lack of a closed transport system is a characteristic feature of earthworms. Choices A, C, and D are incorrect because grasshoppers, dolphins, and chickens have closed circulatory systems where the blood is enclosed within blood vessels, unlike earthworms.
5. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
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