HESI A2
HESI A2 Anatomy and Physiology Practice Test
1. Which of the following is not an example of a nonspecific immune response?
- A. Inflammation
- B. Vasodilation
- C. Release of histamine
- D. Production of antibodies
Correct answer: D
Rationale: The correct answer is D, 'Production of antibodies.' Antibodies are generated as part of the specific immune response, which targets specific antigens. Nonspecific immune responses, such as inflammation, vasodilation, and histamine release, are general defense mechanisms aimed at combating various pathogens. Inflammation is a localized response to infection or injury, vasodilation increases blood flow to the affected area, and histamine release triggers inflammatory responses. It's vital to differentiate between nonspecific responses that provide immediate, general protection and specific responses designed to tackle particular threats.
2. Which vitamin is essential for the synthesis of collagen?
- A. Vitamin C
- B. Vitamin D
- C. Vitamin B12
- D. Vitamin K
Correct answer: A
Rationale: The correct answer is Vitamin C. Vitamin C is essential for the synthesis of collagen, a protein crucial for maintaining the structure and integrity of skin, blood vessels, and bones. It plays a key role in the hydroxylation of proline and lysine residues in collagen synthesis, which is necessary for the stability and strength of collagen fibers. Choice B: Vitamin D is essential for bone health and calcium absorption but is not directly involved in collagen synthesis. Choice C: Vitamin B12 is important for red blood cell formation and neurological function but is not directly related to collagen synthesis. Choice D: Vitamin K is necessary for blood clotting and bone metabolism but does not play a direct role in collagen synthesis.
3. Which organ system is largely responsible for controlling stress?
- A. The endocrine system
- B. The digestive system
- C. The lymphatic system
- D. The respiratory system
Correct answer: A
Rationale: The endocrine system is largely responsible for controlling stress through the release of hormones such as cortisol and adrenaline. These hormones help regulate the body's response to stress by increasing heart rate, blood pressure, and energy production. The endocrine system plays a crucial role in the body's stress response and helps the body adapt to and cope with stressful situations. The digestive system (Choice B) is primarily responsible for breaking down food and absorbing nutrients, not controlling stress. The lymphatic system (Choice C) is responsible for immune function and maintaining fluid balance, not controlling stress. The respiratory system (Choice D) is responsible for the exchange of oxygen and carbon dioxide, not controlling stress.
4. Which feature of the ear is most medial?
- A. Pinna
- B. Tympanic membrane
- C. Cochlea
- D. Outer canal
Correct answer: B
Rationale: The tympanic membrane, also known as the eardrum, is the most medial feature in the ear. It separates the outer ear from the middle ear and serves as a barrier that vibrates in response to sound waves, transmitting vibrations to the middle ear ossicles. The pinna, cochlea, and outer canal are located more laterally in the ear anatomy. The pinna is the visible part of the ear located on the lateral side of the head, the cochlea is a spiral-shaped structure in the inner ear responsible for hearing, and the outer canal refers to the external auditory canal leading to the eardrum.
5. What does trypsin break down in the body?
- A. Fat
- B. Starch
- C. Proteins
- D. Nucleic acids
Correct answer: C
Rationale: Trypsin is an enzyme that specifically breaks down proteins into smaller peptides by hydrolyzing peptide bonds. It is a key enzyme involved in the digestion of proteins in the body, particularly in the small intestine where it helps in the final stages of protein digestion. Choices A, B, and D are incorrect because trypsin does not break down fats, starch, or nucleic acids; its primary function is the digestion of proteins.
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