why is it important to use randomization in a scientific experiment
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HESI PN Nutrition Practice Exam

1. Why is randomization important in a scientific experiment?

Correct answer: B

Rationale: Randomization is crucial in a scientific experiment to eliminate bias in the assignment of subjects to groups. By randomly assigning subjects, it helps ensure that any differences observed in the outcomes are due to the experimental treatment and not to preexisting differences between groups. Choice A is incorrect because randomization does not guarantee representativeness but rather minimizes the impact of confounding variables. Choice C is not entirely accurate; while randomization can contribute to accuracy and validity, its primary purpose is to reduce bias. Choice D is incorrect as the goal of randomization is not to balance the number of subjects but to prevent systematic differences between groups.

2. The parents of a child with sickle cell anemia ask why their child experiences pain. What is the most likely cause?

Correct answer: B

Rationale: In sickle cell anemia, pain is primarily caused by the obstruction of blood flow by sickle-shaped cells. This obstruction leads to inadequate oxygen supply to tissues, resulting in tissue damage and pain. Choice A, inflammation of the vessels, is incorrect as it is not the primary cause of pain in sickle cell anemia. Choice C, overhydration, is unrelated to the pathophysiology of sickle cell anemia and would not lead to the characteristic pain experienced. Choice D, stress-related headaches, is also unrelated to the underlying mechanisms of pain in sickle cell anemia.

3. How does a double-blind experiment work?

Correct answer: B

Rationale: The correct answer is B. In a double-blind experiment, neither the subjects nor the researchers know which subjects are in the control or experimental group. This helps to eliminate bias and ensure that the results are more objective. Choice A is incorrect as in a double-blind experiment, subjects do not take turns receiving each treatment; it is about masking the treatment allocation. Choice C is incorrect because it implies that the researchers are aware of the group allocation, which goes against the principle of blinding in a double-blind study. Choice D is incorrect as both subject groups should not know whether they are in the control or experimental group to maintain the blindness of the study.

4. What is an important dietary consideration for a child with celiac disease?

Correct answer: B

Rationale: A gluten-free diet is crucial for managing celiac disease in children because it helps prevent intestinal damage and alleviate symptoms. Gluten is a protein found in wheat, barley, and rye, and it triggers an immune response in individuals with celiac disease, damaging the lining of the small intestine. Therefore, choices A, C, and D are incorrect. While iron intake is important for overall health, a child with celiac disease can still meet their iron needs through sources that are naturally gluten-free or fortified. A high-protein diet or a low-sodium diet are not specifically required for managing celiac disease.

5. Which medication is typically used for long-term control of asthma?

Correct answer: B

Rationale: The correct answer is B, Theophylline. Theophylline is commonly used for long-term control of asthma by relaxing the muscles around the airways to keep them open, making breathing easier. Albuterol (choice A) is a short-acting bronchodilator for quick relief of asthma symptoms, not for long-term control. Ipratropium (choice C) is another short-acting bronchodilator that helps open the airways but is not typically used for long-term control. Prednisone (choice D) is a corticosteroid usually used for short periods to control asthma exacerbations or flare-ups, not as a long-term control medication.

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