why is it important to use randomization in a scientific experiment
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HESI PN Nutrition Practice Exam

1. Why is randomization important in a scientific experiment?

Correct answer: B

Rationale: Randomization is crucial in a scientific experiment to eliminate bias in the assignment of subjects to groups. By randomly assigning subjects, it helps ensure that any differences observed in the outcomes are due to the experimental treatment and not to preexisting differences between groups. Choice A is incorrect because randomization does not guarantee representativeness but rather minimizes the impact of confounding variables. Choice C is not entirely accurate; while randomization can contribute to accuracy and validity, its primary purpose is to reduce bias. Choice D is incorrect as the goal of randomization is not to balance the number of subjects but to prevent systematic differences between groups.

2. The parents of a child with sickle cell anemia ask why their child experiences pain. What is the most likely cause?

Correct answer: B

Rationale: In sickle cell anemia, pain is primarily caused by the obstruction of blood flow by sickle-shaped cells. This obstruction leads to inadequate oxygen supply to tissues, resulting in tissue damage and pain. Choice A, inflammation of the vessels, is incorrect as it is not the primary cause of pain in sickle cell anemia. Choice C, overhydration, is unrelated to the pathophysiology of sickle cell anemia and would not lead to the characteristic pain experienced. Choice D, stress-related headaches, is also unrelated to the underlying mechanisms of pain in sickle cell anemia.

3. What is the term for the amount of heat required to raise the temperature of one kilogram of water by one degree Celsius?

Correct answer: D

Rationale: The correct answer is D, Kilocalorie. The term kilocalorie, often referred to as a calorie, is the amount of heat required to raise the temperature of one kilogram of water by one degree Celsius. While Choice A, Calorie, is technically correct, it is not the most specific term for the described amount of heat. Choice B, Joule, is a unit of energy but not specifically related to the amount of heat required to raise the temperature of water. Choice C, Kilojoule, is also a unit of energy but not the precise term for the heat required to raise the temperature of water by one degree Celsius.

4. What is an important aspect of care for a child with congenital adrenal hyperplasia?

Correct answer: A

Rationale: The correct answer is A: Monitoring electrolyte levels. In the management of congenital adrenal hyperplasia, it is crucial to monitor electrolyte levels to prevent imbalances and related complications. Restricting physical activity (choice B) is not a typical aspect of care for this condition. Administering high doses of vitamin A (choice C) is not a standard treatment for congenital adrenal hyperplasia and can be harmful in excess. Providing a high-protein diet (choice D) may be beneficial for some conditions but is not a specific requirement for managing congenital adrenal hyperplasia.

5. What is one major weakness of a laboratory-based study?

Correct answer: C

Rationale: One major weakness of laboratory-based studies is that results from animal testing cannot always be applied to human beings. This limitation arises due to the inherent biological differences between animals and humans, making the generalization of findings challenging. While costs may be a concern in some cases, they do not represent a universal weakness of laboratory-based studies. Findings in such studies can be replicated to ensure validity, and experimental variables can be effectively controlled in a laboratory setting. Choice C is the correct answer because the translatability of results from animal studies to humans is a significant challenge in laboratory-based research, impacting the direct application of findings to human health and well-being.

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