which of the following is most likely to develop sickle cell anemia
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HESI Focus on Maternity Exam

1. Which of the following is most likely to develop sickle cell anemia?

Correct answer: C

Rationale: Sickle cell anemia is most commonly found in individuals of African American descent. This is because sickle cell trait provides some protection against malaria, and historically, regions where malaria is or was prevalent have higher rates of sickle cell anemia. Therefore, individuals with African ancestry are at a higher risk of developing sickle cell anemia compared to other populations. Choices A, B, and D are less likely to develop sickle cell anemia due to lower genetic prevalence in their respective populations.

2. When does the fetus typically begin to turn and respond to external stimulation during pregnancy?

Correct answer: B

Rationale: The correct answer is B. The fetus typically begins to respond to external stimulation much later in pregnancy, usually after the first trimester. During the second or third week of pregnancy, the fetus is still in the early stages of development and is not yet capable of turning or responding to external stimuli. Choices A, C, and D are incorrect because they do not accurately reflect the timeline of fetal development when it comes to responding to external stimulation.

3. Jill bears the genetic code for Von Willebrand disease, but she has never developed the illness herself. Jill would be considered:

Correct answer: A

Rationale: Jill is a carrier of the recessive gene for Von Willebrand disease. Being a carrier means that she has one copy of the gene but does not show symptoms of the disease. Carriers can pass on the gene to their offspring. Choice B is incorrect as being a carrier does not mean she is susceptible to developing the disease after adolescence. Choice C is incorrect as 'acceptor' is not a term used in genetics in this context. Choice D is incorrect as susceptibility to the disease is not related to late adulthood in carriers of a recessive gene.

4. What is the process in which the double helix of deoxyribonucleic acid (DNA) duplicates?

Correct answer: B

Rationale: Mitosis is the correct answer because it is the process of cell division in which a cell duplicates its DNA and divides into two identical daughter cells. During mitosis, the DNA is replicated, and each daughter cell receives an identical copy of the genetic material. Amniocentesis is a medical procedure to collect amniotic fluid for prenatal genetic testing and is not related to DNA duplication. Meiosis is a type of cell division that produces gametes with half the genetic material of the parent cell, leading to genetic diversity. Mutation is a permanent alteration in the DNA sequence that can lead to genetic variations but is not the process of DNA duplication.

5. Genotypes are solely based on genetic information.

Correct answer: B

Rationale: The correct answer is B - FALSE. Genotypes are solely based on genetic information and do not reflect environmental influences. Phenotypes, on the other hand, result from the interaction of genetic and environmental factors. Choices A, C, and D are incorrect because genotypes are not influenced by environmental factors, and they are determined by an individual's genetic makeup.

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