HESI LPN
HESI Practice Test Pharmacology
1. A client with a diagnosis of generalized anxiety disorder is prescribed alprazolam. The nurse should instruct the client that this medication may have which potential side effect?
- A. Drowsiness
- B. Dry mouth
- C. Nausea
- D. Headache
Correct answer: A
Rationale: The correct answer is A: Drowsiness. Alprazolam, a medication commonly used to treat anxiety disorders, can cause drowsiness as a common side effect. Clients should be advised not to drive or operate heavy machinery until they know how the medication affects them to ensure their safety.
2. A client is prescribed clopidogrel. The nurse should monitor for which potential side effect of this medication?
- A. Nausea and vomiting
- B. Bleeding or bruising
- C. Gastrointestinal bleeding
- D. Fatigue
Correct answer: C
Rationale: When a client is prescribed clopidogrel, the nurse should monitor for potential side effects related to bleeding due to its antiplatelet effect. Gastrointestinal bleeding is a severe side effect associated with clopidogrel use. Monitoring for signs of gastrointestinal bleeding, such as black, tarry stools or vomiting blood, is essential to prevent serious complications.
3. A client is receiving metronidazole for Clostridium difficile pseudomembranous colitis. Which information should the nurse include in this client's medication teaching plan?
- A. Drink adequate water daily
- B. Take with food
- C. Avoid alcohol consumption
- D. Store medication in the refrigerator
Correct answer: C
Rationale: The correct information to include in the medication teaching plan for a client receiving metronidazole for Clostridium difficile pseudomembranous colitis is to avoid alcohol consumption. Metronidazole can cause a disulfiram-like reaction when combined with alcohol, leading to symptoms such as nausea, vomiting, flushing, and headache. Therefore, it is crucial for the client to abstain from alcohol while taking this medication to prevent adverse effects and ensure treatment effectiveness. Choices A, B, and D are incorrect. Drinking adequate water daily is a general health recommendation but not specific to metronidazole use. Taking with food is not necessary for metronidazole, and in fact, it is recommended to be taken on an empty stomach for better absorption. Storing the medication in the refrigerator is also incorrect, as metronidazole should be stored at room temperature.
4. The client is receiving vancomycin, and the nurse plans to draw blood for a peak and trough to determine... the best timing for these levels?
- A. Midway through administration of the IV dose and 30 minutes before the next
- B. Two hours after completion of the IV dose and 30 minutes before the next
- C. Two hours after completion of the IV dose and one hour before the next
- D. Immediately after completion of the IV dose and 30 minutes before
Correct answer: B
Rationale: To accurately determine peak and trough levels of vancomycin, blood should be drawn two hours after the completion of the IV dose and 30 minutes before the next dose. This timing allows for appropriate assessment of the drug levels in the body, ensuring accurate monitoring of therapeutic and toxic concentrations. Choice A is incorrect as drawing blood midway through administration does not provide an accurate peak level. Choice C is incorrect as drawing blood one hour before the next dose does not represent the trough level. Choice D is incorrect because drawing blood immediately after completion of the IV dose does not allow enough time for the drug to reach peak levels.
5. After receiving the third dose of a new oral anticoagulant prescription, which action should the nurse implement? Select all that apply.
- A. Notify the healthcare provider of the finding
- B. Provide a PRN NSAID for gum discomfort
- C. Review the most recent coagulation lab values
- D. Complete a medication variance report
Correct answer: C
Rationale: Reviewing the most recent coagulation lab values is crucial after receiving multiple doses of a new oral anticoagulant to ensure the patient is within the desired therapeutic range and to prevent adverse events related to over or under-anticoagulation. It is essential to monitor these values closely to adjust the dosage if needed. Notifying the healthcare provider of any concerning findings is important, but it may not be the immediate priority after receiving the third dose. Providing a PRN NSAID for gum discomfort is not typically indicated with oral anticoagulant therapy, as it may increase the risk of bleeding. Completing a medication variance report is more relevant in cases of medication errors or discrepancies, which may not apply in this scenario.
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