HESI LPN
Pharmacology HESI 55 Questions 2023
1. A client receiving enalapril reports a persistent dry cough. The nurse should explain that this side effect is related to which medication action?
- A. It reduces the production of angiotensin II.
- B. It increases the production of angiotensin II.
- C. It causes increased production of bradykinin.
- D. It increases the production of aldosterone.
Correct answer: C
Rationale: The correct answer is C. Enalapril, an ACE inhibitor, inhibits the conversion of angiotensin I to angiotensin II, leading to increased levels of bradykinin. The accumulation of bradykinin is responsible for the persistent dry cough associated with ACE inhibitors like enalapril. Choices A, B, and D are incorrect because enalapril does not directly affect the production of angiotensin II or aldosterone. Instead, it primarily impacts the renin-angiotensin-aldosterone system by inhibiting the conversion of angiotensin I to angiotensin II, leading to bradykinin accumulation.
2. A client is prescribed nitroglycerin sublingual tablets. The practical nurse should reinforce which instruction?
- A. Store the tablets in a cool, dry place.
- B. Take one tablet every 5 minutes until pain is relieved, up to three tablets.
- C. Swallow the tablets whole.
- D. Chew the tablets for faster relief.
Correct answer: A
Rationale: Nitroglycerin sublingual tablets are sensitive to heat and moisture, so they should be stored in a cool, dry place to maintain their efficacy. Storing them in a cool, dry place helps prevent degradation of the medication. Choice B is incorrect because nitroglycerin tablets should be taken as directed by the healthcare provider to avoid potential overdose or adverse effects. Choice C is incorrect because sublingual tablets should be placed under the tongue to dissolve and be absorbed, not swallowed, to ensure their quick action. Choice D is incorrect because sublingual tablets should not be chewed; they are meant to be absorbed through the tissues under the tongue, and chewing them may alter their effectiveness.
3. A client with diabetes mellitus type 2 is prescribed pioglitazone. What instruction should the nurse include in the client's teaching plan?
- A. Report any signs of heart failure.
- B. Take this medication with meals.
- C. Avoid alcohol while taking this medication.
- D. Report any signs of bladder cancer.
Correct answer: A
Rationale: The correct answer is to instruct the client to report any signs of heart failure when taking pioglitazone. Pioglitazone is known to potentially exacerbate heart failure, so it is crucial for clients to monitor and report any symptoms of heart failure promptly to their healthcare provider for appropriate management. Choices B and C are important but not specific to pioglitazone use. Choice D is incorrect as bladder cancer is not a known side effect of pioglitazone.
4. A client with hypertension is prescribed atenolol. The nurse should monitor for which potential side effect?
- A. Bradycardia
- B. Tachycardia
- C. Dry mouth
- D. Hypotension
Correct answer: A
Rationale: When a client is prescribed atenolol, a beta-blocker, the nurse should monitor for bradycardia, which is a potential side effect. Atenolol works by slowing the heart rate, so monitoring the client's heart rate is essential to detect and manage bradycardia promptly.
5. A client is taking levodopa-carbidopa for Parkinson's disease. The nurse should include which instruction when educating the client about this medication?
- A. Increase fluid intake to prevent dehydration.
- B. Take medication with food to improve absorption.
- C. Take medication at bedtime to avoid daytime drowsiness.
- D. It can cause nausea and dizziness.
Correct answer: A
Rationale: The correct instruction for a client taking levodopa-carbidopa for Parkinson's disease is to increase fluid intake to prevent dehydration. Levodopa-carbidopa should be taken with food to reduce gastrointestinal upset and improve absorption. Taking medication at bedtime is not necessary to avoid daytime drowsiness. It is crucial to prevent dehydration due to the medication's side effects. Choice B is incorrect because the medication should be taken with food, not at bedtime. Choice C is incorrect as taking the medication with food, rather than on an empty stomach, aids in absorption and reduces gastrointestinal side effects. Choice D is incorrect as it states the side effects of the medication rather than providing specific instructions on its administration.
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