a client receiving enalapril reports a persistent dry cough the nurse should explain that this side effect is related to which medication action
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Pharmacology HESI 55 Questions 2023

1. A client receiving enalapril reports a persistent dry cough. The nurse should explain that this side effect is related to which medication action?

Correct answer: C

Rationale: The correct answer is C. Enalapril, an ACE inhibitor, inhibits the conversion of angiotensin I to angiotensin II, leading to increased levels of bradykinin. The accumulation of bradykinin is responsible for the persistent dry cough associated with ACE inhibitors like enalapril. Choices A, B, and D are incorrect because enalapril does not directly affect the production of angiotensin II or aldosterone. Instead, it primarily impacts the renin-angiotensin-aldosterone system by inhibiting the conversion of angiotensin I to angiotensin II, leading to bradykinin accumulation.

2. A client with osteoporosis is prescribed raloxifene. The nurse should reinforce which instruction?

Correct answer: A

Rationale: The correct instruction for a client prescribed raloxifene, a medication used for osteoporosis, is to take it at the same time each day. This consistency helps maintain steady blood levels of the medication, enhancing its effectiveness in managing the condition. Choice B is incorrect because raloxifene does not require a full glass of water for administration. Choice C is incorrect as raloxifene should not be taken on an empty stomach. Choice D is incorrect as raloxifene should not be taken immediately after a meal.

3. A client with a history of heart failure is prescribed spironolactone. The nurse should monitor for which potential side effect?

Correct answer: A

Rationale: The correct answer is A: Hyperkalemia. Spironolactone is a potassium-sparing diuretic, which can lead to an excess of potassium in the body, causing hyperkalemia. This medication inhibits the action of aldosterone, leading to decreased potassium excretion and potential retention. Monitoring potassium levels is essential to prevent complications such as cardiac arrhythmias, especially in clients with heart failure.

4. A practical nurse (PN) is preparing to administer enoxaparin to a client. What is the most important action for the PN to take before administering this medication?

Correct answer: B

Rationale: The correct answer is to check the client's platelet count. Enoxaparin can lead to thrombocytopenia (low platelet count), which can increase the risk of bleeding. Therefore, assessing the platelet count before administering enoxaparin is crucial to ensure that it is within a safe range. Assessing the client's blood pressure (Choice A) is not directly related to enoxaparin administration. Monitoring urine output (Choice C) and reviewing blood glucose levels (Choice D) are not essential actions before administering enoxaparin.

5. A client diagnosed with a sinus infection is prescribed ampicillin sodium. The practical nurse (PN) should instruct the client to notify the healthcare provider immediately if which symptom occurs?

Correct answer: A

Rationale: The correct answer is A - Rash. Rash is the most common adverse side effect of all generations of penicillin, indicating an allergy to the medication. An allergic reaction could lead to anaphylactic shock, a severe and potentially life-threatening emergency. It is crucial for the client to inform the healthcare provider promptly if a rash develops after taking ampicillin sodium.

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