HESI LPN
Maternity HESI Practice Questions
1. Which procedure is used to detect neural tube defects such as spina bifida and certain chromosomal abnormalities?
- A. Artificial insemination
- B. Amniocentesis
- C. Endometriosis
- D. Alpha-fetoprotein (AFP) assay
Correct answer: D
Rationale: The correct answer is the Alpha-fetoprotein (AFP) assay. This blood test measures the level of AFP in a pregnant woman's blood, aiding in the detection of neural tube defects and certain chromosomal abnormalities in the fetus. Choice A, artificial insemination, is a method used to facilitate fertilization and is not related to detecting fetal abnormalities. Choice B, amniocentesis, involves collecting amniotic fluid for genetic testing, not directly measuring AFP levels. Choice C, endometriosis, is a medical condition involving abnormal tissue growth and is not a procedure for detecting fetal abnormalities. Therefore, the Alpha-fetoprotein (AFP) assay is the most appropriate option for detecting neural tube defects such as spina bifida and certain chromosomal abnormalities.
2. Thalidomide was marketed in the 1960s as a treatment for:
- A. insomnia and nausea.
- B. infertility and impotence.
- C. Down syndrome.
- D. Turner syndrome.
Correct answer: A
Rationale: Thalidomide was initially marketed as a treatment for insomnia and nausea, particularly in pregnant women. However, it was later found to cause severe birth defects, leading to significant consequences. Choice B, infertility and impotence, is incorrect as thalidomide was not marketed for these conditions. Choices C and D, Down syndrome and Turner syndrome, are genetic conditions and not conditions for which thalidomide was intended as a treatment.
3. In the structure of deoxyribonucleic acid (DNA), which of the following bases combines with thymine?
- A. Cytosine
- B. Adenine
- C. Rhodamine
- D. Serine
Correct answer: B
Rationale: The correct answer is B: Adenine. In the structure of DNA, adenine pairs with thymine through hydrogen bonding, forming one of the complementary base pairs that make up the double helix structure of DNA. Cytosine pairs with guanine, not thymine. Rhodamine and serine are not DNA bases and do not participate in DNA base pairing. Therefore, choices A, C, and D are incorrect.
4. Is Duchenne muscular dystrophy a sex-linked abnormality?
- A. TRUE
- B. FALSE
- C. Sometimes
- D. Always
Correct answer: A
Rationale: The correct answer is A: TRUE. Duchenne muscular dystrophy is an X-linked recessive disorder, primarily affecting males. This is due to the inheritance of the mutated gene on the X chromosome. Choices B, C, and D are incorrect because Duchenne muscular dystrophy is specifically classified as a sex-linked disorder affecting males due to the inheritance pattern.
5. Is color blindness a sex-linked abnormality?
- A. TRUE
- B. FALSE
- C. Sometimes
- D. Always
Correct answer: A
Rationale: The correct answer is A: TRUE. Color blindness is indeed a sex-linked abnormality as it is often associated with genes on the X chromosome. Since males have only one X chromosome, they are more likely to inherit color blindness if the gene is present. This makes color blindness more common in males. Choice B (FALSE) is incorrect because color blindness is linked to the X chromosome. Choices C (Sometimes) and D (Always) are incorrect as color blindness is consistently tied to the X chromosome.
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