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HESI Maternal Newborn
1. Which of the following statements about Rh incompatibility is true?
- A. Rh incompatibility occurs most commonly during a woman’s first pregnancy.
- B. Rh incompatibility is an untreatable condition that leaves a woman infertile for the rest of her life.
- C. Rh incompatibility is an abnormality that is transmitted from generation to generation and carried by a sex chromosome.
- D. Rh incompatibility occurs due to antibodies transmitted to a fetus during subsequent deliveries causing brain damage or death.
Correct answer: D
Rationale: Rh incompatibility occurs when the mother's antibodies attack the fetus's red blood cells, leading to serious complications, usually in subsequent pregnancies. Choice A is incorrect because Rh incompatibility often occurs in subsequent pregnancies, not necessarily the first one. Choice B is incorrect as Rh incompatibility does not render a woman infertile but can lead to complications during pregnancies. Choice C is incorrect as Rh incompatibility is not carried by a sex chromosome but involves the Rh factor on red blood cells.
2. Which of the following statements is true of Down’s syndrome?
- A. Down’s syndrome is usually caused by an extra copy of chromosome 21 in an individual.
- B. The symptoms of Down’s syndrome are similar to those of sickle-cell anemia.
- C. Down’s syndrome is caused by a sexually transmitted infection (STI) during conception.
- D. The probability of having a child with Down’s syndrome increases with the age of the parents.
Correct answer: D
Rationale: The correct answer is D. The likelihood of having a child with Down’s syndrome increases as the age of the parents increases, particularly the mother's age. Choice A is incorrect because Down’s syndrome is caused by an extra copy of chromosome 21, not a defect in the sex chromosomes. Choice B is incorrect as the symptoms of Down’s syndrome and sickle-cell anemia are different. Choice C is also incorrect as Down’s syndrome is not caused by a sexually transmitted infection during conception.
3. When both of the alleles for a trait, such as hair color, are the same, the person is said to be _____ for that trait.
- A. monozygous
- B. dizygous
- C. homozygous
- D. hemizygous
Correct answer: C
Rationale: A person is homozygous for a trait when they have two identical alleles for that trait. In this case, both alleles are the same, indicating a homozygous genotype. Choice A, 'monozygous,' is incorrect as it refers to identical twins originating from a single fertilized egg. Choice B, 'dizygous,' is also incorrect as it refers to fraternal twins or individuals that develop from two separate fertilized eggs. Choice D, 'hemizygous,' is incorrect because it describes a genetic condition where only one allele is present in a diploid organism, typically related to genes on the sex chromosomes.
4. What is a procedure for using ultrasonic sound waves to create a picture of an embryo or fetus?
- A. Phenotype
- B. Sonogram
- C. Genotype
- D. Alpha-fetoprotein (AFP) assay
Correct answer: B
Rationale: A sonogram, also known as an ultrasound, is a procedure that utilizes sound waves to generate images of a developing embryo or fetus. This imaging technique is commonly used in prenatal care to monitor fetal development and identify any potential abnormalities. Choices A, C, and D are incorrect because a phenotype refers to an individual's observable traits resulting from genetic and environmental influences, a genotype is an individual's genetic makeup, and an alpha-fetoprotein (AFP) assay is a blood test used to screen for certain birth defects.
5. Genotypes are solely based on genetic information.
- A. TRUE
- B. FALSE
- C. Sometimes
- D. Never
Correct answer: B
Rationale: The correct answer is B - FALSE. Genotypes are solely based on genetic information and do not reflect environmental influences. Phenotypes, on the other hand, result from the interaction of genetic and environmental factors. Choices A, C, and D are incorrect because genotypes are not influenced by environmental factors, and they are determined by an individual's genetic makeup.
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