what is the term for the study of how diet affects gene expression
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Nutrition Final Exam

1. What is the term for the study of how diet affects gene expression?

Correct answer: B

Rationale: Nutrigenomics is the study of how diet affects gene expression, influencing health outcomes and disease risk. Epigenetics (choice A) involves changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence. Genomics (choice C) is the study of an organism's entire genome. Genetics (choice D) is the study of heredity and the variation of inherited characteristics.

2. What is an important consideration when administering medications to a child with hepatic dysfunction?

Correct answer: B

Rationale: When administering medications to a child with hepatic dysfunction, it is crucial to make adjustments in dosage due to altered metabolism. Hepatic dysfunction can affect the way medications are metabolized in the body, potentially leading to drug toxicity or reduced effectiveness. This is why adjusting the dosage is essential to ensure the medication is both safe and efficient. Choices A, C, and D are incorrect because increasing dosing intervals, avoiding all medications, or using only topical medications do not address the specific issue of altered drug metabolism in hepatic dysfunction.

3. Which of the following is a common complication of an untreated inguinal hernia in children?

Correct answer: B

Rationale: The correct answer is B: Strangulation of the hernia. Untreated inguinal hernias in children can lead to strangulation, which can result in bowel obstruction and ischemia. This is a serious complication that requires prompt medical attention. Choices A, C, and D are incorrect. Gastroenteritis is a gastrointestinal infection that is not directly related to untreated inguinal hernias. Chronic cough is not typically associated with this condition. Epistaxis refers to nosebleeds, which are not a common complication of untreated inguinal hernias in children.

4. What is an important aspect of care for a child with congenital adrenal hyperplasia?

Correct answer: A

Rationale: The correct answer is A: Monitoring electrolyte levels. In the management of congenital adrenal hyperplasia, it is crucial to monitor electrolyte levels to prevent imbalances and related complications. Restricting physical activity (choice B) is not a typical aspect of care for this condition. Administering high doses of vitamin A (choice C) is not a standard treatment for congenital adrenal hyperplasia and can be harmful in excess. Providing a high-protein diet (choice D) may be beneficial for some conditions but is not a specific requirement for managing congenital adrenal hyperplasia.

5. What should be included in the medical management of a sickle cell crisis?

Correct answer: B

Rationale: The correct answer is B: Adequate hydration and pain management. During a sickle cell crisis, it is essential to provide hydration to prevent vaso-occlusive events and manage pain effectively with analgesics. Adequate hydration helps maintain blood flow and prevent further sickling of red blood cells. Pain management is crucial to alleviate the severe pain associated with sickle cell crises. Options A, C, and D are incorrect. Providing information for parents on home care (Option A) may be important for ongoing management but is not specific to an acute crisis. Iron supplements (Option C) are not typically indicated during a sickle cell crisis. Adequate oxygenation and factor VIII (Option D) are not primary interventions for managing a sickle cell crisis; instead, oxygen therapy may be considered in severe cases, and factor VIII is not a standard treatment for sickle cell disease.

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