Nursing Elites

1. Preconception counseling is crucial for the safe management of diabetic pregnancies. Which complication is commonly associated with poor glycemic control before and during early pregnancy?

• A. Frequent episodes of maternal hypoglycemia
• B. Congenital anomalies in the fetus
• C. Hydramnios
• D. Hyperemesis gravidarum

Correct answer: B

Rationale: Preconception counseling is essential as strict metabolic control before conception and in the early weeks of gestation helps reduce the risk of congenital anomalies. Frequent episodes of maternal hypoglycemia usually occur during the first trimester due to hormonal changes, affecting insulin production and use, rather than before conception. Hydramnios is more common in diabetic pregnancies, typically seen in the third trimester, not during early pregnancy. Hyperemesis gravidarum, although it may lead to hypoglycemic events, is related to decreased food intake and glucose transfer to the fetus, exacerbating hypoglycemia rather than being directly associated with poor glycemic control before and during early pregnancy.

2. An individual’s phenotype reflects both genetic and environmental influences.

• A. phenotype
• B. chromosome
• C. allele
• D. genotype

Correct answer: A

Rationale: The correct answer is A: phenotype. A phenotype is the observable characteristics of an individual, which result from the interaction of their genotype with the environment. This interaction between genetics and the environment determines how genes are expressed and how traits are manifested in an individual. Choices B, C, and D are incorrect because chromosomes, alleles, and genotypes are components of an individual's genetic makeup, but they do not directly reflect the observable traits influenced by both genetics and the environment.

3. Which of the following processes happen during mitosis?

• A. Strands of deoxyribonucleic acid (DNA) break apart.
• B. Adenine combines with its appropriate partner, cytosine.
• C. Sperm and ova cells are created.
• D. Twenty-three chromosomes are created.

Correct answer: A

Rationale: The correct process that happens during mitosis is the breaking apart, replication, and division of DNA strands into two new cells, each with the same number of chromosomes as the original cell. Choice B is incorrect because it describes base pairing in DNA, not a process specific to mitosis. Choice C is incorrect as the creation of sperm and ova cells is related to meiosis, not mitosis. Choice D is incorrect because chromosomes are not created during mitosis; they are replicated and divided equally between the daughter cells.

4. After meiosis, each new cell nucleus contains _____ chromosomes.

• A. 46
• B. 35
• C. 23
• D. 12

Correct answer: C

Rationale: After meiosis, each resulting cell contains 23 chromosomes. Meiosis is a process that involves two sequential divisions resulting in four daughter cells, each with half the number of chromosomes as the parent cell. In humans, the parent cell has 46 chromosomes (diploid), and after meiosis, the resulting cells (sperm or ova) have 23 chromosomes (haploid). Choice A (46 chromosomes) is incorrect because this is the number of chromosomes in a human diploid cell before meiosis. Choices B (35 chromosomes) and D (12 chromosomes) are incorrect as they do not represent the correct number of chromosomes after meiosis in human cells.

5. What causes sickle-cell anemia?

• A. A chromosomal abnormality.
• B. A single segment found only on the Y chromosome.
• C. A recessive gene.
• D. A decrease in estrogen levels.

Correct answer: C

Rationale: Sickle-cell anemia is a genetic disorder caused by inheriting two copies of a recessive gene, one from each parent. The correct answer is C. Choice A is incorrect because sickle-cell anemia is not primarily caused by a chromosomal abnormality. Choice B is incorrect as the condition is not linked to a single segment found only on the Y chromosome. Choice D is unrelated as it mentions a decrease in estrogen levels, which is not a cause of sickle-cell anemia.

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