Nursing Elites

1. How do spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

• A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
• B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
• C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
• D. All of the above.

Correct answer: D

Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: Proper attachment of chromosomes to spindle fibers is essential for accurate segregation of genetic material during cell division. Misaligned chromosomes that fail to attach to microtubules can lead to delays in anaphase onset, allowing the cell to correct errors before proceeding with division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores at the centromeres help attach chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, they signal the cell to pause cell cycle progression, ensuring proper chromosome alignment before division. C) Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins: While microtubule dynamics are crucial for cell division, microtubule instability and rapid depolymerization can disrupt chromosome attachment. However, this mechanism is not directly related to the activation of cell cycle checkpoint proteins, making this statement incorrect. Therefore, choices A and B accurately describe how spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints, making option D the correct answer.

2. Which of the following is an example of a salt?

• A. Sodium hydroxide (NaOH)
• B. Hydrochloric acid (HCl)
• C. Sodium chloride (NaCl)
• D. Sulfuric acid (H₂SO₄)

Correct answer: C

Rationale: Sodium chloride (NaCl) is an example of a salt. Salts are ionic compounds formed by the reaction of an acid with a base. In this case, sodium chloride is formed by the reaction of sodium hydroxide (a base) with hydrochloric acid (an acid). Sodium hydroxide (NaOH), hydrochloric acid (HCl), and sulfuric acid (H₂SO₄) are not salts because they are not formed by the neutralization reaction of an acid and a base, which is a characteristic of salts.

3. Which of the following are the two major zones of the respiratory system?

• A. left bronchus and right bronchus
• B. nose and mouth
• C. larynx and pharynx
• D. conducting and respiratory

Correct answer: D

Rationale: The two major zones of the respiratory system are the conducting zone and the respiratory zone. The conducting zone encompasses structures like the nasal cavity, pharynx, larynx, trachea, bronchi, and bronchioles, which serve to transport air into the lungs. On the other hand, the respiratory zone includes the respiratory bronchioles, alveolar ducts, and alveoli, where the crucial gas exchange process between the air in the lungs and the blood occurs. Choices A, B, and C are incorrect as they do not represent the major zones of the respiratory system but rather individual structures within the system.

4. Which molecules are soluble in nonpolar solvents but are hydrophobic?

• A. Carbohydrates
• B. Lipids
• C. Proteins
• D. Nucleic acids

Correct answer: B

Rationale: Lipids are hydrophobic molecules that are soluble in nonpolar solvents like oils but insoluble in water. They consist of fats, oils, waxes, and steroids and play essential roles in energy storage, insulation, and cell membrane structure. Carbohydrates, proteins, and nucleic acids are not typically soluble in nonpolar solvents and do not exhibit the same hydrophobic characteristics as lipids. Carbohydrates are usually hydrophilic and soluble in water, proteins have both hydrophilic and hydrophobic regions but are not generally soluble in nonpolar solvents, and nucleic acids are polar molecules that are not known for their solubility in nonpolar solvents.

5. During swallowing, what is the role of the epiglottis, a small flap of cartilage located near the base of the tongue?

• A. Initiates the swallowing reflex
• B. Grinds food into smaller pieces
• C. Covers the trachea to prevent food aspiration
• D. Stores saliva for lubrication

Correct answer: C

Rationale: The epiglottis plays a crucial role during swallowing by covering the trachea to prevent food or liquid from entering the airway, which could lead to aspiration. By acting as a lid over the trachea, it ensures that food passes down the esophagus to the stomach, preventing it from entering the lungs. Choice A is incorrect as the swallowing reflex is a coordinated muscular action involving the tongue and throat muscles. Choice B is incorrect as grinding food into smaller pieces is primarily the function of the teeth and the initial stages of digestion. Choice D is incorrect as the storage of saliva for lubrication is not a function of the epiglottis, but rather involves salivary glands.

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