HESI LPN
HESI Pharmacology Exam Test Bank
1. A client with type 2 diabetes is prescribed metformin. What instruction should the practical nurse (PN) include in the client's teaching plan?
- A. Take the medication with meals to decrease gastrointestinal upset.
- B. Take the medication with a full glass of water.
- C. Avoid alcohol while taking the medication.
- D. Take the medication with meals to increase absorption.
Correct answer: B
Rationale: The correct instruction for a client prescribed metformin is to take the medication with a full glass of water. This helps ensure proper ingestion and absorption of the medication. While taking metformin with meals can help reduce gastrointestinal side effects, the primary focus should be on adequate hydration and absorption by taking it with water. Avoiding alcohol while taking metformin is also important as alcohol can increase the risk of lactic acidosis when combined with metformin. Taking the medication with meals to increase absorption is incorrect as metformin should be taken with food to reduce gastrointestinal upset, not to increase absorption.
2. A client with osteoporosis is prescribed alendronate. The practical nurse (PN) should reinforce which instruction regarding the administration of this medication?
- A. Take the medication with a full glass of water before breakfast.
- B. Take the medication immediately after a meal.
- C. Lie down for 30 minutes after taking the medication.
- D. Crush the medication and mix it with food.
Correct answer: A
Rationale: The correct instruction for administering alendronate is to take the medication with a full glass of water before breakfast. This timing is crucial to ensure proper absorption in the body and reduce the risk of esophageal irritation. Taking it immediately after a meal or lying down for 30 minutes after may affect absorption and increase the risk of adverse effects. It should not be crushed or mixed with food to maintain its effectiveness.
3. A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client's history, the nurse determines the client has been self-administering St. John's wort, an herbal preparation, on the advice of a friend. What information is most significant about this finding?
- A. Wort can decrease plasma concentration of Cyclospora
- B. Wort can decrease plasma concentration of Tacrolimus
- C. Wort can decrease plasma concentration of Cyclosporine
- D. Wort can decrease plasma concentration of Mycophenolate
Correct answer: C
Rationale: The most significant information about the client self-administering St. John's wort, an herbal preparation, is that it can decrease the plasma concentration of Cyclosporine. St. John's wort is known to reduce the efficacy of Cyclosporine, which is a common immunosuppressant drug used to prevent transplant rejection. Choices A, B, and D are incorrect because St. John's wort does not affect the plasma concentration of Cyclospora, Tacrolimus, or Mycophenolate.
4. What action should be taken six days after starting a prescription for oral amoxicillin solution?
- A. Determine if any other symptoms have developed
- B. Advise the use of over-the-counter antipyretics
- C. Instruct the client to increase oral fluid intake
- D. Ask if the medication has been kept refrigerated
Correct answer: A
Rationale: It is important to monitor for any new symptoms that may indicate a worsening condition or side effects when taking oral amoxicillin solution. This proactive approach helps in assessing the effectiveness and safety of the medication.
5. A client is prescribed clopidogrel. The nurse should monitor for which potential side effect of this medication?
- A. Nausea and vomiting
- B. Bleeding or bruising
- C. Gastrointestinal bleeding
- D. Fatigue
Correct answer: C
Rationale: When a client is prescribed clopidogrel, the nurse should monitor for potential side effects related to bleeding due to its antiplatelet effect. Gastrointestinal bleeding is a severe side effect associated with clopidogrel use. Monitoring for signs of gastrointestinal bleeding, such as black, tarry stools or vomiting blood, is essential to prevent serious complications.
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