HESI LPN
Pharmacology HESI Practice
1. A client who received a renal transplant three months ago is readmitted to the acute care unit with signs of graft rejection. While taking the client's history, the nurse determines the client has been self-administering St. John's wort, an herbal preparation, on the advice of a friend. What information is most significant about this finding?
- A. Wort can decrease plasma concentration of Cyclospora
- B. Wort can decrease plasma concentration of Tacrolimus
- C. Wort can decrease plasma concentration of Cyclosporine
- D. Wort can decrease plasma concentration of Mycophenolate
Correct answer: C
Rationale: The most significant information about the client self-administering St. John's wort, an herbal preparation, is that it can decrease the plasma concentration of Cyclosporine. St. John's wort is known to reduce the efficacy of Cyclosporine, which is a common immunosuppressant drug used to prevent transplant rejection. Choices A, B, and D are incorrect because St. John's wort does not affect the plasma concentration of Cyclospora, Tacrolimus, or Mycophenolate.
2. A client with a diagnosis of schizophrenia is prescribed olanzapine. The nurse should monitor the client for which potential side effect?
- A. Weight gain
- B. Dry mouth
- C. Hair loss
- D. Headache
Correct answer: A
Rationale: The correct answer is A: Weight gain. Olanzapine is known to cause weight gain as a common side effect. This weight gain can increase the risk of metabolic issues such as diabetes and dyslipidemia. Monitoring the client's weight regularly is essential to detect and address any weight changes promptly.
3. A client with diabetes mellitus type 1 is prescribed insulin lispro. When should the nurse instruct the client to administer this medication?
- A. 5-10 minutes before meals
- B. 15 minutes after meals
- C. 30 minutes before meals
- D. 1 hour after meals
Correct answer: A
Rationale: Corrected Rationale: Insulin lispro is a rapid-acting insulin that should be administered 5-10 minutes before meals. This timing helps synchronize the peak action of insulin with the rise in blood glucose levels after eating, effectively managing postprandial hyperglycemia. Choice B, administering 15 minutes after meals, is incorrect because rapid-acting insulins like lispro are meant to act quickly to cover the rise in blood glucose levels after meals. Choices C and D are also incorrect as they do not align with the rapid onset of action required to manage postprandial hyperglycemia in patients with diabetes mellitus type 1.
4. The client is being instructed on the correct technique for using... what to provide the client?
- A. Angle the tip of the inhaler upwards while spraying
- B. Hold one nostril closed while spraying the other nostril
- C. Avoid shaking the inhaler immediately before using
- D. Use the inhaler when first awakening in the morning
Correct answer: B
Rationale: The correct technique for using an inhaler for allergic rhinitis involves holding one nostril closed while spraying the other nostril to ensure proper delivery of the medication. This technique helps direct the medication into the nasal passages for optimal effectiveness. Choice A is incorrect as it refers to an incorrect technique for inhaler use. Choice C is incorrect as shaking the inhaler is often necessary to ensure proper mixing of the medication. Choice D is incorrect as the timing of inhaler use is typically based on individual preferences or healthcare provider recommendations, not specifically tied to the morning.
5. Which assessment finding requires nursing intervention prior to the administration of medication?
- A. Apical pulse heard best at the pulmonic site
- B. Irregular apical pulse rhythm
- C. Presence of a systolic heart murmur
- D. Apical pulse rate of 50 beats/minute
Correct answer: D
Rationale: An apical pulse rate of 50 beats/minute indicates bradycardia, a heart rate below the normal range, which requires immediate nursing intervention before administering medication to address the potential impact of the bradycardia on the patient's overall condition.
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