Nursing Elites

1. What type of inheritance pattern results in a 3:1 ratio of dominant to recessive phenotypes in the F2 generation?

• A. Incomplete dominance
• B. Codominance
• C. Sex-linked inheritance
• D. Autosomal dominant inheritance

Correct answer: D

Rationale: Autosomal dominant inheritance results in a 3:1 ratio of dominant to recessive phenotypes in the F2 generation. This inheritance pattern occurs when a single copy of the dominant allele is enough to express the dominant phenotype. A) Incomplete dominance: In incomplete dominance, the heterozygous phenotype is a blend of the two homozygous phenotypes, and it does not lead to a 3:1 ratio of dominant to recessive phenotypes in the F2 generation. B) Codominance: In codominance, both alleles are fully expressed in the heterozygous phenotype, but this pattern also does not result in a 3:1 ratio of dominant to recessive phenotypes in the F2 generation. C) Sex-linked inheritance: Sex-linked inheritance involves genes located on the sex chromosomes and does not typically lead to a 3:1 ratio of dominant to recessive phenotypes in the F2 generation.

2. What checkpoint mechanism ensures all chromosomes are attached to the spindle fibers before anaphase begins?

• A. Prometaphase
• B. Metaphase
• C. Cyclin degradation
• D. Sister chromatid cohesion

Correct answer: A

Rationale: A) Prometaphase is the correct answer because it is the stage of mitosis where all chromosomes are attached to the spindle fibers before anaphase begins. During prometaphase, the nuclear envelope breaks down, allowing the spindle fibers to attach to the kinetochores of the chromosomes. This attachment is necessary for proper chromosome alignment and segregation during anaphase. B) Metaphase is incorrect because it is the stage where chromosomes are aligned at the metaphase plate but do not necessarily have all spindle fibers attached. C) Cyclin degradation is incorrect because it is a regulatory mechanism that controls the progression of the cell cycle but is not specifically related to ensuring all chromosomes are attached to spindle fibers. D) Sister chromatid cohesion is incorrect because it refers to the physical connection between sister chromatids that is maintained until anaphase, but it does not ensure that all chromosomes are attached to spindle fibers.

3. Which of the following systems does not include a transportation network throughout the body?

• A. Cardiovascular system
• B. Endocrine system
• C. Immune system
• D. Nervous system

Correct answer: B

Rationale: The endocrine system does not include a transportation network throughout the body. While the cardiovascular system transports blood, oxygen, and nutrients, the immune system has lymphatic vessels for immune cell transportation, and the nervous system transmits signals via neurons. In contrast, the endocrine system coordinates bodily functions by releasing hormones directly into the bloodstream, which then act on target organs or tissues. This delivery mechanism is different from the continuous transportation networks found in the other systems listed, making the endocrine system the correct choice for this question.

4. What is a condition characterized by an overactive thyroid gland and excessive production of thyroid hormones called?

• A. Diabetes mellitus
• B. Hyperthyroidism
• C. Hypothyroidism
• D. Cushing's syndrome

Correct answer: B

Rationale: Hyperthyroidism is a condition where the thyroid gland is overactive and produces an excessive amount of thyroid hormones. This can lead to symptoms such as weight loss, rapid heartbeat, sweating, and nervousness. Diabetes mellitus is a condition characterized by high blood sugar levels due to either insufficient insulin production or the body's inability to respond to insulin. Hypothyroidism is the opposite of hyperthyroidism, where the thyroid gland is underactive and produces insufficient thyroid hormones. Cushing's syndrome is a disorder that occurs when the body has a high level of the hormone cortisol for a long time.

5. Which of the following statements is NOT true about DNA?

• A. DNA contains the nucleotides A, T, C, G and is read 5' to 3'.
• B. DNA contains genetic information and is tightly coiled with proteins to form chromosomes.
• C. DNA contains the nucleotides A, T, C, G and is read 3' to 5'.
• D. DNA is a double-stranded molecule connected by hydrogen bonds.

Correct answer: C

Rationale: The correct answer is C because DNA is typically read from the 5' end to the 3' end, not from 3' to 5'. Choices A, B, and D are all true statements about DNA. DNA contains the nucleotides A, T, C, G and is read in a 5' to 3' direction. DNA also contains genetic information and is tightly coiled with proteins to form chromosomes. Additionally, DNA is a double-stranded molecule connected by hydrogen bonds.

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