Nursing Elites

1. What is the significance of studying pedigrees in human genetics?

• A. Predicting the exact outcome of genetic crosses in humans.
• B. Tracing the inheritance of complex traits with multiple contributing genes.
• C. Identifying carriers of dominant genetic disorders.
• D. Determining the risk of acquiring a specific mutation de novo.

Correct answer: B

Rationale: Pedigrees are diagrams that show the relationships within a family and can be used to track the inheritance patterns of specific traits or diseases. While pedigrees can provide information on the inheritance of single gene disorders (such as identifying carriers of dominant genetic disorders, as mentioned in option C), their primary significance lies in studying complex traits with multiple contributing genes. These traits do not follow simple Mendelian inheritance patterns and are influenced by both genetic and environmental factors. By analyzing pedigrees, researchers can identify patterns of inheritance for complex traits, such as polygenic diseases or traits influenced by gene-environment interactions. Therefore, option B is the most appropriate choice as it captures the main significance of studying pedigrees in human genetics.

2. Which types of molecules can move through a cell membrane by passive transport?

• A. Complex sugars
• B. Non-lipid soluble molecules
• C. Oxygen
• D. Molecules moving from areas of low concentration to areas of high concentration

Correct answer: C

Rationale: The correct answer is C: Oxygen. Small, non-polar molecules like oxygen can easily pass through the cell membrane by passive transport as they move down their concentration gradient without the need for energy input. Complex sugars (choice A) are typically too large to pass through the membrane by passive transport. Non-lipid soluble molecules (choice B) may require active transport mechanisms. Choice D describes active transport, where molecules move against their concentration gradient, requiring energy input.

3. Which of the following structures is responsible for preventing the backflow of blood from the left ventricle into the left atrium?

• A. Aortic valve
• B. Pulmonary valve
• C. Tricuspid valve
• D. Mitral valve

Correct answer: D

Rationale: The correct answer is D, the Mitral valve. The mitral valve, also known as the bicuspid valve, is situated between the left atrium and the left ventricle. Its primary function is to prevent the backflow of blood from the left ventricle into the left atrium during ventricular contraction. The other choices are incorrect because: A) The aortic valve prevents backflow from the aorta into the left ventricle. B) The pulmonary valve prevents backflow from the pulmonary artery into the right ventricle. C) The tricuspid valve prevents backflow from the right ventricle into the right atrium.

4. Which vitamin is essential for collagen production, a key component of connective tissues?

• A. Vitamin A
• B. Vitamin C
• C. Vitamin D
• D. Vitamin E

Correct answer: B

Rationale: Vitamin C is essential for collagen production, a key component of connective tissues. Collagen, a crucial protein, provides structure and strength to various body tissues, such as skin, tendons, ligaments, and blood vessels. Vitamin C plays a pivotal role in collagen synthesis by aiding in the hydroxylation of proline and lysine residues, which is essential for stabilizing the collagen structure. A deficiency in vitamin C can lead to impaired collagen production, resulting in conditions like scurvy, characterized by weakened connective tissues. Vitamin A (Choice A) is important for vision and immune function but is not directly involved in collagen production. Vitamin D (Choice C) is essential for calcium absorption and bone health but is not primarily responsible for collagen synthesis. Vitamin E (Choice D) acts as an antioxidant, protecting cells from damage, but it is not a key player in collagen production.

5. Which of the following nucleic acids carries the genetic information copied from DNA to the ribosomes?

• A. DNA
• B. mRNA
• C. rRNA
• D. tRNA

Correct answer: B

Rationale: The correct answer is B: mRNA. Messenger RNA (mRNA) is responsible for carrying the genetic information copied from DNA to the ribosomes for protein synthesis. mRNA serves as a temporary copy of the genetic instructions stored in DNA and acts as a messenger between the nucleus and ribosomes in the cytoplasm where protein synthesis occurs. While rRNA (ribosomal RNA) and tRNA (transfer RNA) play essential roles in the process of translation at the ribosomes, mRNA is the nucleic acid directly involved in carrying the genetic code for protein synthesis. Therefore, choices A, C, and D are incorrect as DNA is the original genetic material, rRNA is a component of the ribosomes, and tRNA carries amino acids during protein synthesis, respectively.

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