Nursing Elites

1. What is the 'lock-and-key' model?

• A. Protein folding
• B. Enzyme-substrate interaction
• C. Muscle contraction
• D. Blood clotting

Correct answer: B

Rationale: The 'lock-and-key' model describes the specificity of the interaction between enzymes and their substrates. In this model, the enzyme's active site acts like a lock that can only be opened by the specific substrate molecule, which serves as the key. This specific binding ensures that enzymes catalyze particular reactions and do not interact with other molecules indiscriminately. Protein folding (option A) is the process by which a protein attains its functional three-dimensional structure but is not directly related to the lock-and-key model. Muscle contraction (option C) and blood clotting (option D) are complex biological processes but are not directly associated with the lock-and-key model of enzyme-substrate interaction.

2. What is the difference between a germline mutation and a somatic mutation?

• A. Germline mutations are passed to offspring, while somatic mutations are not.
• B. Germline mutations occur in reproductive cells, while somatic mutations occur in body cells.
• C. Germline mutations only affect genes, while somatic mutations can affect any DNA.
• D. Germline mutations are always beneficial, while somatic mutations are always harmful.

Correct answer: B

Rationale: Rationale: - Germline mutations are changes in the DNA of reproductive cells (sperm or egg cells) and can be passed on to offspring, affecting all cells in the resulting organism. - Somatic mutations are changes in the DNA of non-reproductive cells (body cells) and are not passed on to offspring. These mutations only affect the cells that arise from the mutated cell. - Option A is incorrect because somatic mutations are not passed to offspring. - Option C is incorrect because both germline and somatic mutations can affect any DNA. - Option D is incorrect because the effects of mutations, whether germline or somatic, can be beneficial, harmful, or have no significant impact.

3. Where does the electron transport chain occur in the cell?

• A. Cytosol
• B. Golgi apparatus
• C. Inner mitochondrial membrane
• D. Nucleus

Correct answer: C

Rationale: The electron transport chain occurs in the inner mitochondrial membrane. This process is crucial for the generation of ATP, the cell's energy currency. Choice A (Cytosol) is incorrect as the electron transport chain does not take place in the cytosol. Choice B (Golgi apparatus) is also incorrect as the Golgi apparatus is involved in modifying, sorting, and packaging of proteins. Choice D (Nucleus) is incorrect as the nucleus houses the cell's genetic material but is not the location of the electron transport chain.

4. Which of the following is an example of a commensal relationship between a microorganism and a human?

• A. Salmonella causing food poisoning
• B. taphylococcus aureus causing skin infections
• C. coli living in the gut
• D. Rabies virus causing neurological disease

Correct answer: C

Rationale: A commensal relationship is a type of symbiotic relationship in which one organism benefits, while the other is neither harmed nor benefited. In this case, E. coli living in the gut is an example of a commensal relationship because it can benefit from the environment in the gut without causing harm to the human host. Option A, Salmonella causing food poisoning, is an example of a pathogenic relationship where the microorganism causes harm to the host. Option B, Staphylococcus aureus causing skin infections, is also an example of a pathogenic relationship where the microorganism causes harm to the host. Option D, Rabies virus causing neurological disease, is another example of a pathogenic relationship where the microorganism causes harm to the host.

5. Which of the following nucleic acids carries amino acids to organelles called ribosomes, where the amino acids are linked one by one to produce a polypeptide?

• A. DNA
• B. mRNA
• C. rRNA
• D. tRNA

Correct answer: D

Rationale: tRNA is the correct answer as it carries amino acids to the ribosomes during protein synthesis. Transfer RNA (tRNA) plays a crucial role in protein synthesis by bringing specific amino acids to the ribosome according to the mRNA sequence. Once at the ribosome, the amino acids are linked together to form a polypeptide chain. This process is essential for the creation of proteins in the cell, highlighting the significance of tRNA in the translation process. Choice A, DNA, is incorrect as DNA does not directly participate in protein synthesis. Choice B, mRNA, is incorrect as mRNA carries the genetic information from DNA to the ribosome but does not directly carry amino acids. Choice C, rRNA, is incorrect as ribosomal RNA is a component of the ribosome structure and is involved in protein synthesis but does not carry amino acids like tRNA.

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