Nursing Elites

1. What checkpoint mechanism ensures all chromosomes are attached to the spindle fibers before anaphase begins?

• A. Prometaphase
• B. Metaphase
• C. Cyclin degradation
• D. Sister chromatid cohesion

Correct answer: A

Rationale: A) Prometaphase is the correct answer because it is the stage of mitosis where all chromosomes are attached to the spindle fibers before anaphase begins. During prometaphase, the nuclear envelope breaks down, allowing the spindle fibers to attach to the kinetochores of the chromosomes. This attachment is necessary for proper chromosome alignment and segregation during anaphase. B) Metaphase is incorrect because it is the stage where chromosomes are aligned at the metaphase plate but do not necessarily have all spindle fibers attached. C) Cyclin degradation is incorrect because it is a regulatory mechanism that controls the progression of the cell cycle but is not specifically related to ensuring all chromosomes are attached to spindle fibers. D) Sister chromatid cohesion is incorrect because it refers to the physical connection between sister chromatids that is maintained until anaphase, but it does not ensure that all chromosomes are attached to spindle fibers.

2. An investigator wishes to test the effect of temperature on the durability of a certain material. He places five blocks of this material in a sunny area in a meadow and five more in a cold area high in the mountains. He then monitors them over time. What is the main problem with this experiment?

• A. Ten subjects are far too small a number to obtain effective results.
• B. It is impossible to control for the fact that the blocks in the mountains were placed later.
• C. There are too many variables that are not being controlled for.
• D. Nothing is wrong with this experiment; this demonstrates good experimental procedure.

Correct answer: C

Rationale: The main problem with this experiment is that there are too many variables that are not being controlled for. The investigator is only changing one variable (temperature) while there are other variables at play such as humidity, exposure to light, and potential differences in the material itself. Without controlling or accounting for these additional variables, it would be difficult to determine if any observed differences in durability are solely due to temperature. Choice A is incorrect because the issue is not solely about the number of subjects but about the lack of control over variables. Choice B is not the main problem as the order of placement may not significantly impact the results. Choice D is incorrect as the experiment lacks proper control over variables, which is a crucial aspect of good experimental procedure.

3. Which organelle is responsible for the final stages of protein modification and packaging for secretion in animal cells?

• A. Rough endoplasmic reticulum (RER)
• B. Smooth endoplasmic reticulum (SER)
• C. Ribosomes
• D. Golgi apparatus

Correct answer: D

Rationale: The Golgi apparatus is responsible for the final stages of protein modification and packaging for secretion in animal cells. After proteins are synthesized in the rough endoplasmic reticulum (RER), they are transported to the Golgi apparatus for further processing, sorting, and packaging before being sent to their final destination within or outside the cell. The smooth endoplasmic reticulum (SER) is mainly involved in lipid metabolism and detoxification processes, not protein modification. Ribosomes are the cellular organelles responsible for protein synthesis, not the final stages of protein modification and packaging for secretion, which is the role of the Golgi apparatus.

4. Which of the following is a representation of a natural pattern or occurrence that is difficult or impossible to experience directly?

• A. A theory
• B. A model
• C. A law
• D. An observation

Correct answer: B

Rationale: A model is a representation of a natural pattern or occurrence that is difficult or impossible to experience directly. Models are used to simplify complex systems or phenomena to aid in understanding or making predictions about them. The other options (A, C, and D) do not specifically refer to representations of natural patterns or occurrences as models do. A theory is an explanation based on observations, experiments, and reasoning. A law is a statement that describes a consistent natural phenomenon observed to occur without exception. An observation is a direct result of perceiving something using the senses, without being a representation or abstraction of a natural pattern.

5. What is the process in which RNA polymerase copies DNA into RNA, with DNA unwinding and serving as a template while RNA is assembled?

• A. Replication
• B. Transcription
• C. Translation
• D. Duplication

Correct answer: B

Rationale: The correct answer is B: Transcription. Transcription is the process where RNA polymerase reads the DNA template strand and synthesizes RNA, following the base-pairing rules. During transcription, DNA unwinds and serves as a template for the assembly of complementary RNA molecules. Replication (Choice A) is the process of making an identical copy of DNA, not RNA from DNA. Translation (Choice C) is the process of synthesizing proteins from mRNA. Duplication (Choice D) is a general term and does not specifically refer to the process described in the question.

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