how does a double blind experiment work
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LPN Nutrition Practice Test

1. How does a double-blind experiment work?

Correct answer: B

Rationale: The correct answer is B. In a double-blind experiment, neither the subjects nor the researchers know which subjects are in the control or experimental group. This helps to eliminate bias and ensure that the results are more objective. Choice A is incorrect as in a double-blind experiment, subjects do not take turns receiving each treatment; it is about masking the treatment allocation. Choice C is incorrect because it implies that the researchers are aware of the group allocation, which goes against the principle of blinding in a double-blind study. Choice D is incorrect as both subject groups should not know whether they are in the control or experimental group to maintain the blindness of the study.

2. The parents of a child with sickle cell anemia ask why their child experiences pain. What is the most likely cause?

Correct answer: B

Rationale: In sickle cell anemia, pain is primarily caused by the obstruction of blood flow by sickle-shaped cells. This obstruction leads to inadequate oxygen supply to tissues, resulting in tissue damage and pain. Choice A, inflammation of the vessels, is incorrect as it is not the primary cause of pain in sickle cell anemia. Choice C, overhydration, is unrelated to the pathophysiology of sickle cell anemia and would not lead to the characteristic pain experienced. Choice D, stress-related headaches, is also unrelated to the underlying mechanisms of pain in sickle cell anemia.

3. What is the term for the amount of heat required to raise the temperature of one kilogram of water by one degree Celsius?

Correct answer: D

Rationale: The correct answer is D, Kilocalorie. The term kilocalorie, often referred to as a calorie, is the amount of heat required to raise the temperature of one kilogram of water by one degree Celsius. While Choice A, Calorie, is technically correct, it is not the most specific term for the described amount of heat. Choice B, Joule, is a unit of energy but not specifically related to the amount of heat required to raise the temperature of water. Choice C, Kilojoule, is also a unit of energy but not the precise term for the heat required to raise the temperature of water by one degree Celsius.

4. You have been asked to help a top nutrition researcher conduct human experiments on vitamin C. As the subjects walk into the laboratory, you distribute all the vitamin C pill bottles to the girls and all the placebo pill bottles to the boys. What should you have done?

Correct answer: D

Rationale: The correct approach in a scientific experiment is to prevent yourself from knowing the contents of the pill bottles and distribute them randomly to the subjects. This randomization helps to avoid bias and ensures that the results are not influenced by preconceived notions. Option A is incorrect because it introduces gender bias by assigning pills based on gender. Option B is incorrect as it mentions telling the subjects what they are getting, which could lead to placebo effects. Option C is incorrect as it suggests disclosing group information to the subjects, which can also introduce bias.

5. How should a caregiver manage a child with a new diagnosis of sickle cell anemia?

Correct answer: B

Rationale: Promoting adequate hydration and pain management is crucial for managing sickle cell anemia to prevent crises and complications. Adequate hydration helps prevent sickling of red blood cells, while effective pain management is essential for addressing the frequent pain episodes associated with the condition. Ensuring the child receives frequent blood transfusions is not the initial management for sickle cell anemia; transfusions are usually reserved for specific complications. Restricting physical activity should be individualized based on the child's condition; some physical activity is beneficial for overall health. Administering high doses of vitamin C is not a standard treatment for sickle cell anemia and does not address the underlying pathology of the disease.

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