Nursing Elites

1. Differentiate between gene therapy and genetic engineering in the context of human intervention.

• A. Gene therapy aims to modify existing genes within body cells, while genetic engineering manipulates genes in embryos to be passed on to offspring.
• B. Gene therapy focuses on treating genetic diseases, while genetic engineering enhances desirable traits or eliminates undesirable ones.
• C. Both involve directly altering the DNA sequence, but gene therapy targets somatic cells and genetic engineering modifies germline cells.
• D. There is no fundamental difference; both terms are synonymous.

Correct answer: B

Rationale: A) Incorrect. Gene therapy does aim to modify existing genes within body cells, but genetic engineering does not necessarily manipulate genes in embryos to be passed on to offspring. Genetic engineering can involve modifying genes in any type of cell, not just embryos. B) Correct. Gene therapy is a medical intervention that aims to treat genetic diseases by correcting or replacing faulty genes within an individual's body cells. On the other hand, genetic engineering involves modifying genes to enhance specific traits or eliminate undesirable ones, often in the context of agriculture or biotechnology. C) Incorrect. While both gene therapy and genetic engineering involve altering DNA sequences, the distinction lies in the target cells. Gene therapy targets somatic cells (non-reproductive cells), while genetic engineering typically involves modifying germline cells (reproductive cells that can pass on genetic changes to offspring). D) Incorrect. There is

2. What is the process in which RNA polymerase copies DNA into RNA, with DNA unwinding and serving as a template while RNA is assembled?

• A. Replication
• B. Transcription
• C. Translation
• D. Duplication

Correct answer: B

Rationale: The correct answer is B: Transcription. Transcription is the process where RNA polymerase reads the DNA template strand and synthesizes RNA, following the base-pairing rules. During transcription, DNA unwinds and serves as a template for the assembly of complementary RNA molecules. Replication (Choice A) is the process of making an identical copy of DNA, not RNA from DNA. Translation (Choice C) is the process of synthesizing proteins from mRNA. Duplication (Choice D) is a general term and does not specifically refer to the process described in the question.

3. What is the term for a genetic disorder caused by a mutation on the X chromosome?

• A. Autosomal dominant disorder
• B. Autosomal recessive disorder
• C. Sex-linked recessive disorder
• D. Sex-linked dominant disorder

Correct answer: C

Rationale: A genetic disorder caused by a mutation on the X chromosome is termed a sex-linked recessive disorder (Option C). This type of disorder is more commonly seen in males due to their single X chromosome, making them more vulnerable to X-linked mutations. Females have two X chromosomes, providing a protective effect against X-linked disorders.\n- Autosomal dominant disorders (Option A) result from a mutation in one copy of a gene on non-sex chromosomes (autosomes) and are not specifically related to the X chromosome.\n- Autosomal recessive disorders (Option B) occur due to mutations in both copies of a gene on autosomes, not on the X chromosome.\n- Sex-linked dominant disorders (Option D) are rare and lead to more severe symptoms in males as they only require one copy of the mutated gene on the X chromosome to express the disorder. However, this is not the term for a genetic disorder caused by an X chromosome mutation.

4. Which of the following substances can donate a hydroxide ion (OH-) in solution?

• A. Salt
• B. Base
• C. Neutral compound
• D. Dehydrating agent

Correct answer: B

Rationale: The correct answer is B: Base. A base is a substance that can donate hydroxide ions (OH-) in solution. Bases increase the concentration of hydroxide ions by either accepting protons (H+) or donating hydroxide ions. Salts are ionic compounds made of cations and anions, which do not directly donate hydroxide ions. Neutral compounds do not significantly affect the concentration of hydroxide ions. Dehydrating agents are substances that remove water molecules from other compounds, unrelated to donating hydroxide ions.

5. Two nursing students will be completing a scientific experiment measuring the mass of chewed gum after one-minute chewing increments. Which lab equipment will the students most likely use?

• A. Triple beam balance
• B. Anemometer
• C. Hot plate
• D. Microscope

Correct answer: A

Rationale: The correct answer is A: Triple beam balance. A triple beam balance is the most suitable lab equipment for measuring mass accurately, which is necessary for this experiment. An anemometer measures wind speed, a hot plate is used for heating substances, and a microscope is used for magnifying objects, none of which are relevant to measuring the mass of chewed gum.

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