a nurse is reviewing a clients medications they include cimetidine and imipramine knowing that cimetidine decreases the metabolism of imipramine the n
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Fundamentals of Nursing HESI

1. A healthcare professional is reviewing a client’s medications. They include cimetidine and imipramine. Knowing that cimetidine decreases the metabolism of imipramine, the healthcare professional should identify that this combination is likely to result in which of the following effects?

Correct answer: B

Rationale: When cimetidine decreases the metabolism of imipramine, it leads to an increased concentration of imipramine in the body, which can result in imipramine toxicity. This increased risk of toxicity is the likely effect of this drug interaction. Choice A is incorrect because cimetidine's effect on imipramine metabolism does not impact the therapeutic effects of cimetidine. Choice C is incorrect because the interaction does not decrease the risk of adverse effects of cimetidine. Choice D is incorrect as the increased concentration of imipramine can lead to toxicity, not increased therapeutic effects.

2. A healthcare professional is preparing to administer an intramuscular injection to a client. Which site is most appropriate for the healthcare professional to use?

Correct answer: B

Rationale: The ventrogluteal site is the most appropriate site for administering an intramuscular injection to an adult client. This site is preferred due to its large muscle mass and distance from major nerves and blood vessels, reducing the risk of injury or complications. The deltoid muscle, while commonly used for vaccinations, may not be suitable for certain medications due to its smaller muscle mass. The dorsogluteal site is no longer recommended due to the proximity of the sciatic nerve, which can lead to complications. The rectus femoris site is not commonly used for intramuscular injections in clinical practice.

3. A nurse is caring for an older, immobile patient whose condition requires a supine position. Which metabolic alteration will the nurse monitor for in this patient?

Correct answer: D

Rationale: When an older, immobile patient is in a supine position, it increases cardiac workload, leading to an increased pulse rate. This is because the heart rate in older adults may not tolerate the additional workload. Choices A, B, and C are incorrect because an increased appetite, increased diarrhea, and increased metabolic rate are not directly associated with being immobile in a supine position. Increased appetite is more related to nutritional needs or certain medical conditions, increased diarrhea could be due to various causes, and an increased metabolic rate is not typically a direct consequence of lying supine.

4. While being educated by a nurse, an assistive personnel (AP) is learning about proper hand hygiene. Which statement made by the AP indicates a good understanding of the teaching?

Correct answer: C

Rationale: Choice C is the correct answer because it demonstrates an understanding that soap and water should be used when hands are visibly dirty or when dealing with specific pathogens. Choice A is incorrect because it suggests the use of soap and water over alcohol-based hand rub without specifying the circumstances. Choice B is incorrect as it implies that using alcohol-based hand rub after using the restroom is always suitable. Choice D is incorrect because it states that hand rub is always enough, which is not true when hands are visibly soiled or when specific pathogens are present.

5. UAP has lowered the head of the bed to change the linens for a client who is bedridden. Which observation...most immediate intervention by the nurse?

Correct answer: D

Rationale: The correct answer is D. Purulent drainage around the insertion site of the feeding tube indicates an infection, which requires immediate attention. This may be a sign of a serious complication that needs prompt nursing intervention to prevent further complications or deterioration in the client's condition. Choices A, B, and C do not indicate an immediate threat to the client's health. While option A highlights the infusion rate of the feeding, it does not pose an immediate risk compared to the presence of purulent drainage indicating infection.

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