ATI LPN
LPN Pharmacology Practice Test
1. A client is receiving heparin therapy. Which of the following laboratory tests should be monitored to evaluate the effectiveness of the therapy?
- A. Prothrombin time (PT)
- B. International normalized ratio (INR)
- C. Activated partial thromboplastin time (aPTT)
- D. Complete blood count (CBC)
Correct answer: C
Rationale: Activated partial thromboplastin time (aPTT) is the most appropriate laboratory test to monitor the effectiveness of heparin therapy. Heparin works on the intrinsic pathway of the coagulation cascade, and monitoring aPTT helps assess its anticoagulant effect. Therapeutic levels of aPTT for clients on heparin therapy are typically 1.5 to 2.5 times the control value. Prothrombin time (PT) and International normalized ratio (INR) are used to monitor warfarin therapy, which acts on the extrinsic pathway of the coagulation cascade. Complete blood count (CBC) is not specific for monitoring the effectiveness of heparin therapy.
2. The client with a history of heart failure is receiving digoxin (Lanoxin). Which electrolyte imbalance increases the risk of digoxin toxicity?
- A. Hypernatremia
- B. Hypercalcemia
- C. Hypokalemia
- D. Hypomagnesemia
Correct answer: C
Rationale: Hypokalemia increases the risk of digoxin toxicity as low potassium levels enhance the effects of digoxin on the heart, leading to toxicity and potential adverse effects. Hypernatremia (Choice A) is not directly associated with an increased risk of digoxin toxicity. Hypercalcemia (Choice B) does not increase the risk of digoxin toxicity. Hypomagnesemia (Choice D) can contribute to digoxin toxicity, but hypokalemia has a more significant impact on increasing the risk.
3. The client is receiving furosemide (Lasix) for heart failure. What potential side effect should the nurse monitor for?
- A. Hypokalemia
- B. Hyperkalemia
- C. Hypernatremia
- D. Hypoglycemia
Correct answer: A
Rationale: The correct answer is A: Hypokalemia. Furosemide, a loop diuretic, causes potassium loss, leading to hypokalemia. Monitoring potassium levels is crucial because hypokalemia can result in cardiac arrhythmias and muscle weakness. Choices B, C, and D are incorrect because furosemide does not typically cause hyperkalemia, hypernatremia, or hypoglycemia.
4. A client has been prescribed ciprofloxacin and is receiving discharge teaching. Which of the following instructions should be included by the healthcare provider?
- A. Take the medication with milk.
- B. Avoid exposure to sunlight.
- C. Take the medication at bedtime.
- D. Increase your intake of vitamin K.
Correct answer: B
Rationale: The correct answer is to instruct the client to avoid exposure to sunlight. Ciprofloxacin can increase the risk of photosensitivity, making it important to protect the skin from sunlight to prevent skin reactions. This precaution can help prevent skin damage and discomfort in individuals taking ciprofloxacin. Choices A, C, and D are incorrect. Taking ciprofloxacin with milk is not recommended as it may reduce the absorption of the medication. There is no specific instruction to take ciprofloxacin at bedtime. Increasing vitamin K intake is not directly related to ciprofloxacin therapy.
5. The LPN/LVN is assisting in the care of a client who has been prescribed enoxaparin (Lovenox) for the prevention of deep vein thrombosis (DVT). Which instruction should the nurse reinforce with the client?
- A. Avoid consuming foods high in vitamin K while taking this medication.
- B. Administer the injection in the same site each time for consistency.
- C. Report any unusual bleeding or bruising to your healthcare provider.
- D. Do not take aspirin if you experience any mild pain or discomfort.
Correct answer: C
Rationale: The correct instruction for the nurse to reinforce with the client is to report any unusual bleeding or bruising to their healthcare provider. This is crucial because unusual bleeding or bruising may indicate excessive anticoagulation, a potential side effect of enoxaparin. Prompt reporting to a healthcare provider is necessary to prevent complications. Choices A, B, and D are incorrect. Choice A is not directly related to enoxaparin and vitamin K interactions. Choice B is incorrect as rotating injection sites is essential for preventing tissue damage and irritation. Choice D is also incorrect as aspirin can increase the risk of bleeding when taken with enoxaparin.
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