HESI LPN
Pharmacology HESI 2023
1. A 6-month-old infant is prescribed digoxin for the treatment of congestive heart failure. Which observation by the practical nurse (PN) warrants immediate intervention for signs of digoxin toxicity?
- A. Apical heart rate of 60 beats/min
- B. Sweating across the forehead
- C. Poor sucking effort
- D. Respiratory rate of 30 breaths/min
Correct answer: A
Rationale: A heart rate of 60 beats/min for a 6-month-old infant warrants immediate intervention as it falls below the normal range. The normal heart rate for a 6-month-old is 80 to 150 beats/min when awake, and a rate of 70 beats/min while sleeping is considered within normal limits. Bradycardia (heart rate <60 beats/min) in infants can be a sign of digoxin toxicity, necessitating prompt evaluation and intervention to prevent adverse effects. Sweating across the forehead (Choice B) is a non-specific symptom and may not directly indicate digoxin toxicity. Poor sucking effort (Choice C) and a respiratory rate of 30 breaths/min (Choice D) are not typically associated with digoxin toxicity and do not require immediate intervention in the context of this question.
2. Which assessment finding indicates that the expected outcome of administering donepezil to a client with Alzheimer's disease has been accomplished?
- A. Increased muscle strength and tone
- B. Fewer episodes of urinary incontinence
- C. Decreased confusion and improved mood
- D. Reversal of the disease process as evidenced by increased functioning
Correct answer: C
Rationale: The correct answer is C. Donepezil is a medication used for individuals with Alzheimer's disease. Its mechanism of action involves increasing acetylcholine levels by inhibiting its breakdown, which benefits cognitive function. The expected outcome of administering donepezil is a decrease in confusion and an improvement in mood due to the medication's impact on neurotransmitters. Choices A, B, and D are incorrect because donepezil does not primarily target muscle strength, urinary incontinence, or disease reversal; instead, it aims to slow down the progression of cognitive decline in Alzheimer's disease.
3. A client with rheumatoid arthritis is prescribed tofacitinib. What should the nurse include in the client's teaching plan?
- A. Avoid live vaccines while taking this medication.
- B. Take this medication with food to decrease gastrointestinal upset.
- C. Report any signs of infection to the healthcare provider.
- D. Avoid sunlight while taking this medication.
Correct answer: A
Rationale: Tofacitinib is an immunosuppressive medication used in rheumatoid arthritis. Patients taking tofacitinib should avoid live vaccines because the medication can weaken the immune system, making live vaccines potentially harmful. It is essential to educate the client on this to prevent any complications related to live vaccines during their treatment.
4. A client with severe rheumatoid arthritis is prescribed adalimumab. The nurse should monitor for which potential adverse effect?
- A. Increased risk of infection
- B. Bone marrow suppression
- C. Hair loss
- D. Hyperglycemia
Correct answer: A
Rationale: The correct answer is A: Increased risk of infection. Adalimumab is known to increase the risk of infection due to its immunosuppressive effects. Patients on adalimumab should be closely monitored for signs and symptoms of infection, such as fever, chills, and malaise, and should promptly report any such symptoms to their healthcare provider for further evaluation and management. Monitoring for infection is crucial to prevent serious complications in patients receiving adalimumab therapy.
5. A client with anxiety is prescribed alprazolam. What instruction should the nurse include in the client's teaching plan?
- A. Take this medication with food.
- B. Avoid activities that require alertness.
- C. Do not stop taking this medication abruptly.
- D. This medication may cause drowsiness.
Correct answer: C
Rationale: The correct answer is C: 'Do not stop taking this medication abruptly.' Alprazolam should not be stopped suddenly as it can lead to withdrawal symptoms. It is important for clients to taper off the medication gradually under medical supervision to prevent adverse effects. Choices A, B, and D are incorrect. Choice A is irrelevant to alprazolam administration instructions. Choice B, 'Avoid activities that require alertness,' is not the priority teaching point for alprazolam. Choice D, 'This medication may cause drowsiness,' is a common side effect of alprazolam but not the most critical instruction to include in the teaching plan.
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