Nursing Elites

1. Which of the following functions is not controlled by the autonomic nervous system?

• A. Digestion
• B. Walking
• C. Heartbeat
• D. Temperature regulation

Correct answer: B

Rationale: The correct answer is B: Walking. Walking is not directly controlled by the autonomic nervous system. Walking is a voluntary action governed by the somatic nervous system, which controls voluntary skeletal muscle movement. The autonomic nervous system, on the other hand, regulates functions that are involuntary, such as digestion, heartbeat, and temperature regulation. Choices A, C, and D are all functions controlled by the autonomic nervous system. Digestion involves processes like peristalsis and secretion of digestive enzymes, heartbeat is regulated by the autonomic nervous system to maintain blood pressure and circulation, and temperature regulation includes responses like sweating or shivering to maintain body temperature within a narrow range.

2. The ureters are paired tubes that transport urine from the:

• A. Bladder to the urethra
• B. Kidneys to the bladder
• C. Urethra to the kidneys
• D. Skin to the kidneys

Correct answer: B

Rationale: The ureters are responsible for carrying urine from the kidneys to the bladder. Once urine is produced in the kidneys, it travels down the ureters to be stored in the bladder until it is eliminated from the body through the urethra. Therefore, the correct answer is B, 'Kidneys to the bladder.' Choices A, C, and D are incorrect as they do not accurately describe the function of the ureters in the urinary system. Choice A, 'Bladder to the urethra,' is incorrect because the ureters carry urine from the kidneys to the bladder, not from the bladder to the urethra. Choice C, 'Urethra to the kidneys,' is incorrect as the flow of urine is from the kidneys to the bladder via the ureters, not in the reverse direction. Choice D, 'Skin to the kidneys,' is unrelated to the urinary system; the ureters are not involved in transporting substances from the skin to the kidneys.

3. What is the main function of the endoplasmic reticulum (ER) in the cell?

• A. To synthesize and transport proteins and lipids
• B. To package and transport proteins
• C. To break down macromolecules
• D. To store genetic material

Correct answer: A

Rationale: The endoplasmic reticulum (ER) is a network of membranes within the cell that plays a crucial role in protein and lipid synthesis. It consists of two types: rough ER, which is studded with ribosomes and involved in protein synthesis, and smooth ER, which is involved in lipid synthesis and detoxification. The ER's main function is to synthesize proteins and lipids, not just package and transport them. While the ER is involved in transporting these synthesized proteins and lipids to other parts of the cell or outside the cell, its primary role is in their synthesis. Breaking down macromolecules is primarily the function of lysosomes, which are membrane-bound organelles containing enzymes for digestion. Storing genetic material is the function of the nucleus, which houses the cell's DNA. The ER is not involved in storing genetic material.

4. Calcitonin, a hormone that helps regulate calcium levels, is produced by the:

• A. Thyroid gland
• B. Parathyroid gland
• C. Thymus gland
• D. Adrenal gland

Correct answer: A

Rationale: Calcitonin is a hormone produced by the thyroid gland. It helps regulate calcium levels in the body by inhibiting the breakdown of bone and promoting calcium excretion by the kidneys. The parathyroid gland produces parathyroid hormone (PTH), which works in opposition to calcitonin to regulate calcium levels. The thymus gland is involved in the development of the immune system, and the adrenal gland produces hormones such as cortisol and adrenaline. Therefore, the correct answer is the thyroid gland as it specifically secretes calcitonin for calcium regulation.

5. How do spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

• A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
• B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
• C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
• D. All of the above.

Correct answer: D

Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: Proper attachment of chromosomes to spindle fibers is essential for accurate segregation of genetic material during cell division. Misaligned chromosomes that fail to attach to microtubules can lead to delays in anaphase onset, allowing the cell to correct errors before proceeding with division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores at the centromeres help attach chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, they signal the cell to pause cell cycle progression, ensuring proper chromosome alignment before division. C) Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins: While microtubule dynamics are crucial for cell division, microtubule instability and rapid depolymerization can disrupt chromosome attachment. However, this mechanism is not directly related to the activation of cell cycle checkpoint proteins, making this statement incorrect. Therefore, choices A and B accurately describe how spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints, making option D the correct answer.

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