Nursing Elites

1. Which of the following terms describes the enlargement of an organ or tissue?

• A. Dystrophy
• B. Atrophy
• C. Hypertrophy
• D. Eutrophy

Correct answer: C

Rationale: Hypertrophy refers to the enlargement of an organ or tissue, typically due to an increase in the size of individual cells. This can occur in response to increased workload, hormonal stimulation, or other factors. On the other hand, dystrophy refers to the degeneration and deterioration of tissue, atrophy describes the decrease in the size of an organ or tissue, and eutrophy denotes a state of normal nutrition or growth. Therefore, the correct answer is 'Hypertrophy' as it specifically relates to the increase in size or volume of an organ or tissue.

2. Which organ in the human body is the largest and is responsible for detoxification, metabolism, and storage of nutrients?

• A. Heart
• B. Liver
• C. Lungs
• D. Skin

Correct answer: B

Rationale: The liver is the largest internal organ in the human body and is responsible for detoxification, metabolism, storage of nutrients, and various other essential functions. It plays a critical role in maintaining overall health by processing nutrients, filtering blood, and detoxifying harmful substances. While the skin is the largest organ by surface area, the liver is the largest internal organ and is crucial for various physiological processes. The heart is responsible for pumping blood, the lungs for respiration, and the skin for protection and temperature regulation, but they do not perform the functions specified in the question.

3. Which macromolecule will always contain nitrogen?

• A. Fatty acid
• B. Protein
• C. Lipid
• D. Carbohydrate

Correct answer: B

Rationale: The correct answer is B: Protein. Proteins always contain nitrogen, as it is a key element in amino acids, the building blocks of proteins. Fatty acids (choice A), lipids (choice C), and carbohydrates (choice D) do not always contain nitrogen. Fatty acids consist of long chains of hydrocarbons, lipids are mainly composed of carbon, hydrogen, and oxygen, and carbohydrates are composed of carbon, hydrogen, and oxygen as well, but not nitrogen.

4. How do spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints?

• A. Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset.
• B. The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression.
• C. Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins.
• D. All of the above.

Correct answer: D

Rationale: A) Misaligned chromosomes fail to attach to microtubules, triggering a delay in anaphase onset: Proper attachment of chromosomes to spindle fibers is essential for accurate segregation of genetic material during cell division. Misaligned chromosomes that fail to attach to microtubules can lead to delays in anaphase onset, allowing the cell to correct errors before proceeding with division. B) The presence of unattached kinetochores on the centromeres sends a signal to pause cell cycle progression: Kinetochores at the centromeres help attach chromosomes to spindle fibers. When kinetochores are unattached or improperly attached to microtubules, they signal the cell to pause cell cycle progression, ensuring proper chromosome alignment before division. C) Microtubule instability and rapid depolymerization lead to the activation of checkpoint proteins: While microtubule dynamics are crucial for cell division, microtubule instability and rapid depolymerization can disrupt chromosome attachment. However, this mechanism is not directly related to the activation of cell cycle checkpoint proteins, making this statement incorrect. Therefore, choices A and B accurately describe how spindle fiber dynamics and microtubule attachment regulate cell cycle checkpoints, making option D the correct answer.

5. What is the role of the spleen in the body?

• A. To produce bile
• B. To filter blood and remove old red blood cells
• C. To produce red blood cells
• D. To store fat

Correct answer: B

Rationale: The correct answer is B. The spleen acts as a blood filter, removing old or damaged red blood cells. It also plays a role in immune responses, storing blood reserves, and helping to fight infection. The production of bile is primarily associated with the liver, not the spleen. While the bone marrow is responsible for red blood cell production, the spleen's main functions do not include this process. Storing fat is not a primary function of the spleen.

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