Nursing Elites

1. What potential consequences can chromosomal nondisjunction have on offspring?

• A. Down syndrome, caused by an extra copy of chromosome 21.
• B. Turner syndrome, characterized by the absence of one X chromosome in females.
• C. Klinefelter syndrome, featuring one or more extra X chromosomes in males.
• D. All of the above.

Correct answer: D

Rationale: - Chromosomal nondisjunction is the failure of homologous chromosomes or sister chromatids to separate properly during cell division, leading to an abnormal number of chromosomes in the resulting cells. - Down syndrome is caused by an extra copy of chromosome 21, resulting from nondisjunction during meiosis. Individuals with Down syndrome have three copies of chromosome 21 instead of the usual two. - Turner syndrome is characterized by the absence of one X chromosome in females, leading to a variety of physical and developmental features. - Klinefelter syndrome features one or more extra X chromosomes in males, typically resulting in infertility and other physical characteristics. Therefore, chromosomal nondisjunction can lead to various genetic disorders such as Down syndrome, Turner syndrome, and Klinefelter syndrome, making option D the correct answer.

2. Which of the following is NOT a component of the body's innate immune response?

• A. Physical barriers like skin and mucous membranes
• B. Phagocytes that engulf and destroy pathogens
• C. Inflammatory response to isolate and contain infection
• D. Production of antibodies specific to a particular pathogen

Correct answer: D

Rationale: The production of antibodies specific to a particular pathogen is a function of the adaptive immune response, not the innate immune response. Innate immunity involves nonspecific defense mechanisms like physical barriers, phagocytes, and inflammation, which provide immediate protection against pathogens without prior exposure. Antibody production is a characteristic of adaptive immunity, where the body generates specific antibodies in response to encountering a pathogen for the first time. Therefore, option D is the correct answer as it does not align with the immediate and nonspecific nature of the innate immune response.

3. What is the function of the lymphatic system?

• A. To transport oxygen
• B. To filter waste from the blood
• C. To produce red blood cells
• D. To regulate body temperature

Correct answer: B

Rationale: The correct answer is B: 'To filter waste from the blood.' The lymphatic system is responsible for draining excess fluid from tissues, absorbing fats from the digestive system, and filtering out harmful substances and waste products from the blood. It also plays a crucial role in the body's immune defense by transporting white blood cells and antibodies to fight off infections. Choices A, C, and D are incorrect because transporting oxygen, producing red blood cells, and regulating body temperature are functions performed by other systems in the body, such as the respiratory system, bone marrow, and thermoregulatory mechanisms, respectively.

4. What is the difference between a homozygous recessive genotype and a homozygous dominant genotype?

• A. Both have the same phenotype, but different genotypes.
• B. Both have the same genotype, but different phenotypes.
• C. Homozygous recessive has two dominant alleles, while homozygous dominant has two recessive alleles.
• D. Homozygous recessive has two identical recessive alleles, while homozygous dominant has two identical dominant alleles.

Correct answer: D

Rationale: - Homozygous recessive genotype refers to an individual having two identical recessive alleles for a particular gene (e.g., rr for a trait where r represents the recessive allele). - Homozygous dominant genotype refers to an individual having two identical dominant alleles for a particular gene (e.g., RR for a trait where R represents the dominant allele). - The difference between the two genotypes lies in the specific alleles present in each case, with homozygous recessive having two recessive alleles and homozygous dominant having two dominant alleles. - This genetic difference results in different phenotypes being expressed, as the dominant allele typically masks the expression of the recessive allele in heterozygous individuals.

5. DNA has both a 'sense' and 'antisense' strand. What is true about the antisense strand?

• A. It runs 5' to 3'.
• B. It runs 3' to 5'.
• C. It is used in replication.
• D. It is the direction DNA is stored.

Correct answer: B

Rationale: The correct answer is B: 'It runs 3' to 5'. The antisense strand runs in the 3' to 5' direction, complementing the sense strand. Choice A is incorrect as the antisense strand runs in the opposite direction, which is 3' to 5'. Choice C is incorrect because the antisense strand is not directly involved in replication. Choice D is incorrect as the direction DNA is stored is not determined by the antisense strand.

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