Nursing Elites

1. What is the difference between polygenic inheritance and pleiotropy?

• A. Polygenic inheritance involves multiple genes influencing one trait, while pleiotropy involves one gene affecting multiple traits.
• B. Polygenic inheritance is found in simple Mendelian traits, while pleiotropy is found in complex traits.
• C. Polygenic inheritance is always quantitative, while pleiotropy can be qualitative or quantitative.
• D. Both involve multiple genes and multiple traits, but the specific mechanisms differ

Correct answer: A

Rationale: - Polygenic inheritance refers to the situation where a trait is influenced by multiple genes, each contributing a small effect to the phenotype. These traits often show continuous variation and are not easily categorized into discrete categories. - Pleiotropy, on the other hand, occurs when a single gene influences multiple, seemingly unrelated traits. This means that a mutation in one gene can lead to multiple phenotypic effects across different traits or characteristics. - Therefore, the key difference between polygenic inheritance and pleiotropy lies in the number of genes involved in influencing a trait (multiple genes in polygenic inheritance vs. one gene in pleiotropy) and the direction of influence (one trait affected by multiple genes in polygenic inheritance vs. multiple traits affected by one gene in pleiotropy).

2. Antigenic variation, a common strategy used by some viruses, allows them to:

• A. Produce toxins
• B. Evade the immune system
• C. Survive outside a host
• D. Replicate rapidly

Correct answer: B

Rationale: Antigenic variation is a strategy used by some viruses to evade the host's immune response. By constantly changing their surface antigens, viruses can avoid recognition and destruction by the immune system. This allows the virus to persist in the host and continue replicating, leading to prolonged infection and potential transmission to other hosts. Antigenic variation does not directly involve the production of toxins, survival outside a host, or rapid replication, making options A, C, and D incorrect in this context.

3. What is the main function of calcitonin, a hormone produced by the thyroid gland?

• A. Stimulate metabolism and heat production
• B. Increase calcium absorption from the intestines
• C. Enhance bone growth and development
• D. Lower blood calcium levels

Correct answer: D

Rationale: Calcitonin is a hormone produced by the thyroid gland that primarily functions to lower blood calcium levels. It achieves this by inhibiting bone breakdown and promoting calcium excretion by the kidneys. Therefore, the correct answer is D as it reflects the main role of calcitonin in calcium homeostasis. Choices A, B, and C are incorrect as they do not align with the primary function of calcitonin. Calcitonin does not stimulate metabolism and heat production (Choice A), increase calcium absorption from the intestines (Choice B), or enhance bone growth and development (Choice C).

4. What is the term for the chemical reaction that involves the loss of electrons?

• A. Reduction
• B. Oxidation
• C. Neutralization
• D. Precipitation

Correct answer: B

Rationale: Oxidation is the process where a substance loses electrons. In an oxidation reaction, the substance being oxidized loses electrons, which are gained by another substance. Reduction is the opposite process, where a substance gains electrons. Neutralization is a reaction between an acid and a base to form a salt and water. Precipitation is the formation of a solid from a solution. Therefore, in the context of a chemical reaction involving the loss of electrons, the correct term is oxidation (Choice B).

5. What is the structure that attaches to each chromosome during mitosis?

• A. Centromere
• B. Telomere
• C. Spindle apparatus
• D. Nucleolus

Correct answer: A

Rationale: The correct answer is the centromere. It is the structure that attaches to each chromosome during mitosis. The centromere serves as the attachment point for spindle fibers during cell division, ensuring proper distribution of chromosomes to daughter cells. Telomeres are found at the ends of chromosomes, providing protection and stability. The spindle apparatus is responsible for separating chromosomes during cell division. The nucleolus, located within the nucleus, is involved in ribosomal RNA synthesis and not in chromosome attachment during mitosis.

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