Nursing Elites

1. What enzymes do lysosomes contain, leading to their nickname as the cell's 'suicide bags'?

• A. Hydrolytic enzymes
• B. Ligases (bonding enzymes)
• C. Transferases (molecule transfer)
• D. Oxidoreductases (redox reactions)

Correct answer: A

Rationale: Lysosomes are organelles filled with hydrolytic enzymes that break down proteins, nucleic acids, lipids, and carbohydrates. These enzymes aid in digesting cellular waste and foreign substances, hence the term 'suicide bags' due to their involvement in cell degradation and recycling. Ligases are enzymes that catalyze the joining of two large molecules by forming a new chemical bond, not present in lysosomes. Transferases are enzymes that catalyze the transfer of functional groups from one molecule to another, not found in lysosomes. Oxidoreductases are enzymes involved in oxidation-reduction reactions, which are not the primary function of lysosomes.

2. From an anterior view, which of the following vessels carries blood away from the heart?

• A. Left common carotid artery
• B. Pulmonary trunk
• C. Subclavian arteries
• D. All of the above

Correct answer: D

Rationale: The correct answer is D, 'All of the above.' When viewed from an anterior perspective, the left common carotid artery, pulmonary trunk, and subclavian arteries all carry blood away from the heart. The left common carotid artery supplies oxygenated blood to the head and neck, the pulmonary trunk carries deoxygenated blood to the lungs for oxygenation, and the subclavian arteries transport blood to the upper extremities. Therefore, all the vessels listed in the choices are correct as they function to carry blood away from the heart when viewed anteriorly.

3. Parkinson's disease is a neurodegenerative disorder affecting which neurotransmitter?

• A. Dopamine
• B. Acetylcholine
• C. Serotonin
• D. Glutamate

Correct answer: A

Rationale: Parkinson's disease is primarily caused by the loss of dopamine-producing neurons in the brain. Dopamine is a neurotransmitter that plays a crucial role in coordinating movement. The reduction of dopamine levels leads to the characteristic motor symptoms of Parkinson's disease, such as tremors, rigidity, and bradykinesia. Choice B, acetylcholine, is involved in functions like muscle contraction and autonomic nervous system regulation but is not primarily affected in Parkinson's disease. Serotonin (Choice C) is involved in mood regulation and sleep, not the main neurotransmitter affected in Parkinson's disease. Glutamate (Choice D) is the major excitatory neurotransmitter in the central nervous system and is not primarily implicated in Parkinson's disease pathophysiology.

4. Which of the following is the main organ responsible for producing enzymes?

• A. Liver
• B. Pancreas
• C. Stomach
• D. Small intestine

Correct answer: B

Rationale: The main organ responsible for producing enzymes is the pancreas. Enzymes are proteins that act as biological catalysts to speed up chemical reactions in the body. The pancreas produces and releases digestive enzymes that help break down carbohydrates, proteins, and fats in the small intestine to aid in the digestion and absorption of nutrients. While the liver also plays a role in producing bile, which helps in the digestion and absorption of fats, the primary organ responsible for producing enzymes is the pancreas. The stomach produces gastric juices containing hydrochloric acid and pepsin to help break down food, but it is not the primary organ for enzyme production. The small intestine is where most nutrient digestion and absorption occur; however, it receives enzymes from organs like the pancreas rather than producing them itself.

5. Which type of mutation involves a change in the number of chromosomes?

• A. Point mutation
• B. Frameshift mutation
• C. Missense mutation
• D. Aneuploidy

Correct answer: D

Rationale: A) Point mutation involves a change in a single nucleotide base pair within the DNA sequence. B) Frameshift mutation involves the insertion or deletion of nucleotides, causing a shift in the reading frame of the genetic code. C) Missense mutation involves a single nucleotide change that results in a codon that codes for a different amino acid. D) Aneuploidy involves a change in the number of chromosomes, where an individual may have an extra chromosome (trisomy) or a missing chromosome (monosomy). Aneuploidy can lead to genetic disorders such as Down syndrome (trisomy 21) or Turner syndrome (monosomy X). Changing the number of chromosomes is a characteristic feature of aneuploidy, making it the correct answer. Point mutation, frameshift mutation, and missense mutation do not involve a change in the number of chromosomes and are focused on alterations at the nucleotide level within the DNA sequence.

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