ATI LPN
LPN Pharmacology Practice Test
1. A client has a new prescription for levothyroxine. Which of the following instructions should the nurse include?
- A. Take the medication on an empty stomach.
- B. Take the medication with food.
- C. Take the medication at bedtime.
- D. Take the medication with an antacid.
Correct answer: A
Rationale: The correct answer is A: 'Take the medication on an empty stomach.' Levothyroxine should be taken on an empty stomach to ensure optimal absorption. Food, especially high-fiber foods, can interfere with the absorption of levothyroxine. Taking it with an antacid or at bedtime may also affect its absorption. Instructing the client to take the medication on an empty stomach will help maintain consistent blood levels of levothyroxine. Choice B is incorrect as taking levothyroxine with food can reduce its absorption. Choice C is incorrect because taking levothyroxine at bedtime may lead to inconsistent blood levels due to food intake during the day. Choice D is incorrect as antacids can interfere with the absorption of levothyroxine.
2. The client with a history of heart failure is receiving digoxin (Lanoxin). Which electrolyte imbalance increases the risk of digoxin toxicity?
- A. Hypernatremia
- B. Hypercalcemia
- C. Hypokalemia
- D. Hypomagnesemia
Correct answer: C
Rationale: Hypokalemia increases the risk of digoxin toxicity as low potassium levels enhance the effects of digoxin on the heart, leading to toxicity and potential adverse effects. Hypernatremia (Choice A) is not directly associated with an increased risk of digoxin toxicity. Hypercalcemia (Choice B) does not increase the risk of digoxin toxicity. Hypomagnesemia (Choice D) can contribute to digoxin toxicity, but hypokalemia has a more significant impact on increasing the risk.
3. A hypertensive client who has been taking metoprolol (Lopressor) has been prescribed to decrease the dose of the medication. The client asks the nurse why this must be done over a period of 1 to 2 weeks. In formulating a response, the nurse incorporates the understanding that abrupt withdrawal could affect the client in which way?
- A. Result in hypoglycemia
- B. Give the client insomnia
- C. Precipitate rebound hypertension
- D. Cause enhanced side effects of other prescribed medications
Correct answer: C
Rationale: Abruptly stopping metoprolol can lead to rebound hypertension, causing a sudden increase in blood pressure due to the sudden withdrawal of the medication. Gradually tapering the dose helps the body adjust and reduces the risk of this adverse effect. Choices A, B, and D are incorrect. Stopping metoprolol suddenly is not known to result in hypoglycemia, insomnia, or enhanced side effects of other medications.
4. A client with chronic heart failure is being discharged with a prescription for digoxin (Lanoxin). Which instruction should the nurse reinforce?
- A. Take the medication at the same time each day.
- B. Avoid foods high in potassium.
- C. Skip a dose if you feel well.
- D. Take the medication on an empty stomach.
Correct answer: A
Rationale: Taking digoxin at the same time each day is essential to maintain a consistent blood level of the medication. This consistency helps optimize the therapeutic effects of digoxin in managing chronic heart failure. Deviating from the scheduled time could lead to fluctuations in drug levels, affecting its effectiveness and potentially causing harm. Choices B, C, and D are incorrect because avoiding potassium-rich foods, skipping doses when feeling well, and taking the medication on an empty stomach are not relevant or appropriate instructions for a client prescribed digoxin.
5. The client has been prescribed warfarin (Coumadin) and is being educated about dietary restrictions. Which food should the client be advised to avoid or eat in consistent amounts?
- A. Bananas
- B. Spinach
- C. Oranges
- D. Yogurt
Correct answer: B
Rationale: Spinach is high in vitamin K, which can interfere with the effectiveness of warfarin. It is important for clients taking warfarin to maintain consistent levels of vitamin K intake to ensure the medication works properly. Foods rich in vitamin K, such as spinach, can counteract the effects of warfarin, leading to potential complications. Therefore, clients on warfarin are advised to either avoid or consume vitamin K-rich foods, like spinach, in consistent amounts to maintain the medication's efficacy. Bananas, oranges, and yogurt are not high in vitamin K and do not significantly impact the effectiveness of warfarin, making them safe options for clients taking this medication.
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