a client with rheumatoid arthritis is prescribed methotrexate the nurse should monitor for which common side effect of this medication
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HESI Practice Test Pharmacology

1. A client with rheumatoid arthritis is prescribed methotrexate. The nurse should monitor for which common side effect of this medication?

Correct answer: A

Rationale: The correct answer is A: Liver toxicity. Methotrexate is known to cause liver toxicity, making regular monitoring of liver function essential. Monitoring liver function tests helps detect any signs of liver damage early, allowing for appropriate interventions to be implemented promptly.

2. A client with diabetes mellitus is prescribed insulin glargine. What information should the practical nurse (PN) provide to the client about this medication?

Correct answer: B

Rationale: Insulin glargine is a long-acting insulin that should not be mixed with other insulins in the same syringe. Mixing it with other insulins can alter its pharmacokinetics and effectiveness. Insulin glargine is usually administered at the same time each day, often at bedtime, to provide a consistent basal level of insulin over 24 hours.

3. A client with asthma is prescribed montelukast. The nurse should instruct the client that this medication is used for which purpose?

Correct answer: B

Rationale: Montelukast is a leukotriene receptor antagonist used for the long-term control of asthma symptoms by reducing inflammation in the airways. It is not typically used for immediate relief during acute asthma attacks, where short-acting bronchodilators are more appropriate. Montelukast does not specifically target exercise-induced bronchospasm or allergic rhinitis symptoms. Therefore, the correct answer is B. Choice A is incorrect because montelukast is not for immediate relief of acute asthma attacks. Choice C is incorrect as montelukast is not primarily used to treat exercise-induced bronchospasm. Choice D is incorrect because montelukast is not indicated for immediate relief of allergic rhinitis symptoms.

4. A practical nurse is reviewing the medication administration record for a client prescribed prednisone. What potential side effect should the nurse monitor for?

Correct answer: C

Rationale: Prednisone, a corticosteroid, can cause side effects such as hypertension, fluid retention, and weight gain. Hypertension is a common side effect of prednisone due to its impact on sodium and fluid retention in the body. Monitoring blood pressure is crucial to detect and manage hypertension in clients taking prednisone. Choices A, B, and D are incorrect. While prednisone can indirectly affect blood glucose levels, hypoglycemia is not a common side effect. Weight gain, not weight loss, is more prevalent with prednisone use. Diarrhea is not a typical side effect associated with prednisone.

5. What information should the practical nurse provide to a female client who started taking an oral sulfonamide for a urinary tract infection the previous day and reports slight anorexia, while also experiencing urinary frequency?

Correct answer: C

Rationale: The practical nurse should advise the client to take sulfonamides with a full glass of water to help prevent crystalluria. It is essential to take the medication on an empty stomach, ideally 1 hour before eating or 2 hours after eating to maximize its absorption and effectiveness. Continuing to drink cranberry juice is beneficial, but it is important to take the medicine separately to enhance its therapeutic action.

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