HESI LPN
Pharmacology HESI 2023
1. A client is prescribed methylprednisolone for an allergic reaction. The nurse should monitor for which potential side effect of this medication?
- A. Nausea and vomiting
 - B. Weight gain
 - C. Insomnia
 - D. Increased appetite
 
Correct answer: B
Rationale: When a client is prescribed methylprednisolone, a corticosteroid, the nurse should monitor for weight gain as a potential side effect. Corticosteroids like methylprednisolone can cause weight gain and fluid retention due to their impact on metabolism and sodium retention. Nausea and vomiting are less common side effects of methylprednisolone. Insomnia and increased appetite are not typically associated with methylprednisolone use.
2. A client with a diagnosis of schizophrenia is prescribed clozapine. The nurse should monitor the client for which potential side effect?
- A. Agranulocytosis
 - B. Dry mouth
 - C. Weight gain
 - D. Hypersalivation
 
Correct answer: A
Rationale: The correct answer is Agranulocytosis. Clozapine is known to potentially cause agranulocytosis, a serious condition characterized by a dangerously low white blood cell count. Monitoring white blood cell counts is crucial to detect this side effect early and prevent complications. Choices B, C, and D are incorrect because dry mouth, weight gain, and hypersalivation are not typically associated with clozapine use. While dry mouth can be a common side effect of some antipsychotic medications, it is not specifically linked to clozapine. Weight gain can occur with certain antipsychotics, but clozapine is more commonly associated with metabolic side effects. Hypersalivation is not a common side effect of clozapine.
3. A client with a diagnosis of generalized anxiety disorder is prescribed buspirone. The nurse should include which instruction in the client's teaching plan?
- A. This medication may cause drowsiness; avoid driving.
 - B. This medication may take several weeks to take effect.
 - C. This medication can be taken on an as-needed basis.
 - D. This medication should be taken with food.
 
Correct answer: B
Rationale: Buspirone may take several weeks to take effect, so clients should continue taking it as prescribed and not expect immediate relief.
4. A client with a history of deep vein thrombosis is prescribed edoxaban. The nurse should monitor for which potential adverse effect?
- A. Increased risk of bleeding
 - B. Decreased risk of bleeding
 - C. Increased risk of infection
 - D. Decreased risk of infection
 
Correct answer: A
Rationale: The correct answer is A: Increased risk of bleeding. Edoxaban is an anticoagulant that works by inhibiting clot formation, thereby increasing the risk of bleeding. Therefore, the nurse should closely monitor the client for signs of bleeding, such as bruising, petechiae, hematuria, or gastrointestinal bleeding, to prevent potential complications. Choices B, C, and D are incorrect because edoxaban does not decrease the risk of bleeding or affect the risk of infection; its primary concern is the potential for bleeding due to its anticoagulant properties.
5. A client who is newly diagnosed with erosive esophagitis secondary to GERD experiences symptoms after taking lansoprazole PO for one full week. Which actions should the nurse take?
- A. Confirm that the client is taking the medication correctly
 - B. Auscultate the client's bowel sounds and assess the apical pulse
 - C. Advise the client that healing typically takes several weeks
 - D. Notify the healthcare provider to consider a higher dose
 
Correct answer: C
Rationale: The correct action for the nurse to take in this situation is to advise the client that healing from erosive esophagitis typically takes several weeks. Providing this information helps manage the client's expectations and anxiety about treatment effectiveness. It is not necessary to confirm medication timing, assess bowel sounds, or measure the apical pulse at this point. Since symptoms persist after one week of lansoprazole, it may not be appropriate to immediately escalate to a higher dose without further assessment or guidance from the healthcare provider. Auscultating bowel sounds and assessing the apical pulse are not relevant to the client's symptoms related to erosive esophagitis and GERD.
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