Nursing Elites

1. Which type of mutation involves a change in the number of chromosomes?

• A. Point mutation
• B. Frameshift mutation
• C. Missense mutation
• D. Aneuploidy

Correct answer: D

Rationale: A) Point mutation involves a change in a single nucleotide base pair within the DNA sequence. B) Frameshift mutation involves the insertion or deletion of nucleotides, causing a shift in the reading frame of the genetic code. C) Missense mutation involves a single nucleotide change that results in a codon that codes for a different amino acid. D) Aneuploidy involves a change in the number of chromosomes, where an individual may have an extra chromosome (trisomy) or a missing chromosome (monosomy). Aneuploidy can lead to genetic disorders such as Down syndrome (trisomy 21) or Turner syndrome (monosomy X). Changing the number of chromosomes is a characteristic feature of aneuploidy, making it the correct answer. Point mutation, frameshift mutation, and missense mutation do not involve a change in the number of chromosomes and are focused on alterations at the nucleotide level within the DNA sequence.

2. Which of the following terms refers to a muscle that lengthens while another muscle contracts to produce movement?

• A. Synergist
• B. Agonist
• C. Antagonist
• D. Flexor

Correct answer: C

Rationale: The correct answer is 'Antagonist.' An antagonist muscle is a muscle that lengthens while another muscle (agonist) contracts to produce movement. The antagonist muscle relaxes to allow the agonist muscle to contract effectively. In this scenario, the antagonist muscle works in opposition to the agonist muscle, providing control and precision to movement. The other choices are incorrect because a synergist muscle assists the agonist muscle in performing a movement, an agonist muscle is the primary muscle responsible for generating movement, and a flexor muscle is a muscle that decreases the angle at a joint.

3. What is the oxidation state of carbon in CH4?

• A. +1
• B. -1
• C. +2
• D. -4

Correct answer: D

Rationale: In CH4 (methane), carbon is bonded to four hydrogen atoms. Hydrogen has an oxidation state of +1. Since the overall charge of CH4 is 0, the oxidation state of carbon must be -4 to balance the charges. Each hydrogen contributes an oxidation state of +1, resulting in a total of +4 from hydrogen atoms. To achieve a total oxidation state of 0 for the molecule, carbon must have an oxidation state of -4 to offset the contribution from hydrogen. Therefore, the correct answer is -4. Choices A, B, and C are incorrect: +1 is the oxidation state of hydrogen, -1 is not the oxidation state of carbon in methane, and +2 is not the correct oxidation state of carbon in CH4.

4. What is the significance of studying pedigrees in human genetics?

• A. Predicting the exact outcome of genetic crosses in humans.
• B. Tracing the inheritance of complex traits with multiple contributing genes.
• C. Identifying carriers of dominant genetic disorders.
• D. Determining the risk of acquiring a specific mutation de novo.

Correct answer: B

Rationale: Pedigrees are diagrams that show the relationships within a family and can be used to track the inheritance patterns of specific traits or diseases. While pedigrees can provide information on the inheritance of single gene disorders (such as identifying carriers of dominant genetic disorders, as mentioned in option C), their primary significance lies in studying complex traits with multiple contributing genes. These traits do not follow simple Mendelian inheritance patterns and are influenced by both genetic and environmental factors. By analyzing pedigrees, researchers can identify patterns of inheritance for complex traits, such as polygenic diseases or traits influenced by gene-environment interactions. Therefore, option B is the most appropriate choice as it captures the main significance of studying pedigrees in human genetics.

5. Which type of cell division is responsible for growth and repair?

• A. Meiosis
• B. Mitosis
• C. Binary fission
• D. Osmosis

Correct answer: B

Rationale: Mitosis is the correct type of cell division responsible for growth and repair. During mitosis, a cell divides to produce two identical daughter cells, contributing to growth and tissue repair in multicellular organisms. Meiosis, on the other hand, is involved in the formation of gametes (sperm and egg cells) for sexual reproduction. Binary fission is a form of asexual reproduction in single-celled organisms, and osmosis is the movement of water molecules across a selectively permeable membrane. Therefore, choices A, C, and D are incorrect as they are not directly related to growth and repair in multicellular organisms.

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