Nursing Elites

1. What is the major difference between somatic and germline mutations?

• A. Somatic mutations usually benefit the individual while germline mutations usually harm them.
• B. Since germline mutations only affect one cell, they are less noticeable than the rapidly dividing somatic cells.
• C. Somatic mutations are not expressed for several generations, but germline mutations are expressed immediately.
• D. Germline mutations are usually inherited while somatic mutations will affect only the individual.

Correct answer: D

Rationale: The major difference between somatic and germline mutations is that germline mutations are usually inherited and can be passed on to offspring, while somatic mutations occur in non-reproductive cells and only affect the individual in which they occur. This means that germline mutations have the potential to be present in future generations, while somatic mutations do not.

2. What do hair follicles house in the skin?

• A. Blood vessels (Blood vessels are not housed within hair follicles)
• B. Nerve endings (Nerve endings are present but not housed within hair follicles)
• C. Hair shafts and hair roots
• D. Sebaceous glands (These glands are often attached to hair follicles)

Correct answer: C

Rationale: Hair follicles are structures in the skin that contain the hair shaft (the visible part of the hair) and the hair root (the part of the hair beneath the skin). The hair shaft is the portion of the hair that is visible above the skin, while the hair root is the part that extends below the surface into the follicle. Therefore, the correct answer is that hair follicles house the hair shafts and hair roots. Choices A, B, and D are incorrect because blood vessels are not housed within hair follicles, nerve endings are present but not housed within hair follicles, and sebaceous glands are often attached to hair follicles but not housed within them.

3. Which of the following is directly transcribed from DNA and represents the first step in protein synthesis?

• A. siRNA
• B. rRNA
• C. mRNA
• D. tRNA

Correct answer: C

Rationale: mRNA (messenger RNA) is directly transcribed from DNA in the nucleus during the process of transcription. It serves as a template for protein synthesis during translation in the cytoplasm. mRNA carries genetic information from the DNA to the ribosomes, where it determines the sequence of amino acids in a protein. Thus, mRNA represents the first step in protein synthesis as it carries the code from the DNA to be translated into a protein. Choice A, siRNA (small interfering RNA), is involved in post-transcriptional gene silencing and does not play a role in protein synthesis. Choice B, rRNA (ribosomal RNA), is a component of the ribosome and plays a structural and functional role in protein synthesis but is not directly transcribed from DNA. Choice D, tRNA (transfer RNA), is responsible for bringing amino acids to the ribosome during protein synthesis but is not directly transcribed from DNA.

4. Which type of RNA carries the genetic code from DNA to ribosomes?

• A. Ribosomal RNA (rRNA)
• B. Transfer RNA (tRNA)
• C. Messenger RNA (mRNA)
• D. Deoxyribonucleic acid (DNA)

Correct answer: C

Rationale: - Messenger RNA (mRNA) carries the genetic information from DNA in the cell's nucleus to the ribosomes in the cytoplasm, where protein synthesis occurs. - Ribosomal RNA (rRNA) is a component of the ribosomes where protein synthesis takes place. - Transfer RNA (tRNA) is responsible for bringing amino acids to the ribosomes during protein synthesis. - Deoxyribonucleic acid (DNA) is the genetic material that contains the instructions for building and maintaining an organism. DNA is transcribed into mRNA before being translated into proteins.

5. Myelin sheath is a fatty substance that insulates and protects the long extensions of some nerve cells. It is produced by:

• A. Schwann cells
• B. Astrocytes
• C. Neurons
• D. Oligodendrocytes

Correct answer: A

Rationale: Schwann cells are indeed responsible for producing the myelin sheath in the peripheral nervous system. These cells wrap around axons to form the myelin sheath, which enhances the speed of nerve impulse conduction. In the central nervous system, oligodendrocytes are responsible for producing the myelin sheath. Astrocytes provide support and maintenance functions for neurons, while neurons are the nerve cells themselves and do not produce myelin. Therefore, the correct answer is Schwann cells as they are specifically involved in myelin production in the peripheral nervous system.

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