Nursing Elites

1. Which hormone primarily triggers ovulation in the female menstrual cycle?

• A. Estrogen
• B. Progesterone
• C. Luteinizing hormone (LH)
• D. Follicle-stimulating hormone (FSH)

Correct answer: C

Rationale: Luteinizing hormone (LH) is the hormone primarily responsible for triggering ovulation in the female menstrual cycle. LH surge occurs around the middle of the menstrual cycle, causing the mature follicle to release an egg from the ovary. Estrogen and progesterone play crucial roles in regulating the menstrual cycle and preparing the endometrium for potential implantation of a fertilized egg, but they do not trigger ovulation directly. Follicle-stimulating hormone (FSH) is essential for the development of ovarian follicles but is not the primary hormone responsible for ovulation. Therefore, the correct answer is Luteinizing hormone (LH) as it directly initiates the release of the egg during ovulation.

2. Which of the following statements is correct based on anatomical terms?

• A. The shoulder joint is proximal to the neck.
• B. The elbow joint is superior to the shoulder.
• C. The thoracic vertebrae are superior to the cervical vertebrae.
• D. The thumb is on the lateral aspect of the hand.

Correct answer: D

Rationale: Option D is the correct answer based on anatomical terms. The thumb is indeed located on the lateral aspect of the hand, following anatomical positioning. The terms 'proximal,' 'superior,' and 'inferior' are used in relation to the center of the body or a specific point of reference, while 'lateral' and 'medial' describe positions further away or closer to the midline of the body. Therefore, the thumb being on the lateral side of the hand is an accurate anatomical description. Choices A, B, and C are incorrect because they do not align with anatomical terminology. In anatomical terms, 'proximal' refers to a position closer to the center of the body, 'superior' indicates a position above or higher than another part, and 'inferior' signifies a position below or lower than another part. The shoulder joint is distal to the neck, the elbow is inferior to the shoulder, and the cervical vertebrae are superior to the thoracic vertebrae.

3. What checkpoint mechanism ensures all chromosomes are attached to the spindle fibers before anaphase begins?

• A. Prometaphase
• B. Metaphase
• C. Cyclin degradation
• D. Sister chromatid cohesion

Correct answer: A

Rationale: A) Prometaphase is the correct answer because it is the stage of mitosis where all chromosomes are attached to the spindle fibers before anaphase begins. During prometaphase, the nuclear envelope breaks down, allowing the spindle fibers to attach to the kinetochores of the chromosomes. This attachment is necessary for proper chromosome alignment and segregation during anaphase. B) Metaphase is incorrect because it is the stage where chromosomes are aligned at the metaphase plate but do not necessarily have all spindle fibers attached. C) Cyclin degradation is incorrect because it is a regulatory mechanism that controls the progression of the cell cycle but is not specifically related to ensuring all chromosomes are attached to spindle fibers. D) Sister chromatid cohesion is incorrect because it refers to the physical connection between sister chromatids that is maintained until anaphase, but it does not ensure that all chromosomes are attached to spindle fibers.

4. The 'fight-or-flight' response is triggered by the hormone released from the:

• A. Thyroid gland
• B. Adrenal glands
• C. Pituitary gland
• D. Pancreas

Correct answer: B

Rationale: The 'fight-or-flight' response is triggered by the release of adrenaline (epinephrine) and norepinephrine from the adrenal glands. These hormones prepare the body to either confront or flee from a perceived threat or stressor. The adrenal glands are crucial in initiating this rapid physiological response. Choices A, C, and D are incorrect because the thyroid gland primarily regulates metabolism and energy levels, the pituitary gland controls other endocrine glands but does not directly trigger the 'fight-or-flight' response, and the pancreas is responsible for regulating blood sugar levels through insulin and glucagon, not for triggering the 'fight-or-flight' response.

5. Which type of mutation involves a change in the number of chromosomes?

• A. Point mutation
• B. Frameshift mutation
• C. Missense mutation
• D. Aneuploidy

Correct answer: D

Rationale: A) Point mutation involves a change in a single nucleotide base pair within the DNA sequence. B) Frameshift mutation involves the insertion or deletion of nucleotides, causing a shift in the reading frame of the genetic code. C) Missense mutation involves a single nucleotide change that results in a codon that codes for a different amino acid. D) Aneuploidy involves a change in the number of chromosomes, where an individual may have an extra chromosome (trisomy) or a missing chromosome (monosomy). Aneuploidy can lead to genetic disorders such as Down syndrome (trisomy 21) or Turner syndrome (monosomy X). Changing the number of chromosomes is a characteristic feature of aneuploidy, making it the correct answer. Point mutation, frameshift mutation, and missense mutation do not involve a change in the number of chromosomes and are focused on alterations at the nucleotide level within the DNA sequence.

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