Nursing Elites

1. The body's first line of defense against pathogens is the innate immune system. Which of the following is NOT a component of the innate immune system?

• A. Physical barriers like skin and mucous membranes
• B. Phagocytes that engulf and destroy pathogens
• C. Inflammatory response to isolate and contain infection
• D. Production of antibodies specific to a particular pathogen

Correct answer: D

Rationale: The production of antibodies specific to a particular pathogen is a function of the adaptive immune system, not the innate immune system. The innate immune system provides immediate, non-specific defense mechanisms against pathogens, including physical barriers, phagocytes, and inflammatory responses. Choices A, B, and C are all correct components of the innate immune system. Physical barriers like skin and mucous membranes act as the first line of defense, preventing pathogens from entering the body. Phagocytes are specialized cells that engulf and destroy pathogens, while the inflammatory response helps isolate and contain infections to prevent their spread.

2. What is the role of RNA interference in silencing genes?

• A. Increases protein production
• B. Promotes gene mutation
• C. Inhibits the expression of specific genes
• D. Repairs damaged DNA

Correct answer: C

Rationale: RNA interference (RNAi) is a biological process that involves the silencing of gene expression by inhibiting the translation of mRNA or by degrading mRNA molecules. This mechanism plays a crucial role in regulating gene expression and can be used to selectively silence specific genes. By interfering with the expression of specific genes, RNAi can downregulate protein production from those genes. Therefore, option C, 'Inhibits the expression of specific genes,' is the correct role of RNA interference in silencing genes. Options A, B, and D are incorrect because RNA interference does not increase protein production, promote gene mutation, or repair damaged DNA; its primary function is to inhibit gene expression by degrading or interfering with mRNA.

3. Which of the following lobes of the brain is responsible for sensation, perception, and spatial reasoning?

• A. Frontal
• B. Occipital
• C. Parietal
• D. Temporal

Correct answer: C

Rationale: The parietal lobe is responsible for sensation, perception, and spatial reasoning. It plays a crucial role in processing sensory information, assisting in spatial orientation, and integrating various sensory inputs to create a comprehensive perception of the surrounding environment. The frontal lobe, although important for higher cognitive functions and motor skills, is not primarily responsible for sensation, perception, or spatial reasoning. The occipital lobe is mainly involved in visual processing, and the temporal lobe is primarily associated with auditory processing, memory, and emotions, making them incorrect choices for this question.

4. What property of a substance remains constant regardless of changes in its shape or size?

• A. Mass
• B. Weight
• C. Density
• D. Volume

Correct answer: A

Rationale: Mass is a measure of the amount of matter in an object and remains constant regardless of changes in its shape or size. Weight, density, and volume can all change depending on the conditions, but mass remains the same. For example, if you have a piece of clay and you shape it into a ball or flatten it into a pancake, the amount of clay (mass) will remain the same, even though the shape and size have changed. Weight is the force acting on an object due to gravity, which can vary depending on the gravitational pull. Density is the mass per unit volume, so it changes with variations in volume. Volume is the amount of space occupied by an object, which can change if the shape or size of the object is altered.

5. What is the process of breaking down glucose into pyruvate called?

• A. Glycolysis
• B. Gluconeogenesis
• C. Krebs cycle
• D. Oxidative phosphorylation

Correct answer: A

Rationale: A) Glycolysis is the process of breaking down glucose into pyruvate. This occurs in the cytoplasm of cells and is the first step in cellular respiration. B) Gluconeogenesis is the process of synthesizing glucose from non-carbohydrate sources, such as amino acids or glycerol, and is the opposite of glycolysis. C) The Krebs cycle, also known as the citric acid cycle, is a series of chemical reactions that occur in the mitochondria and is involved in the oxidation of acetyl-CoA to produce ATP and other energy carriers. D) Oxidative phosphorylation is the final stage of cellular respiration where ATP is produced through the transfer of electrons in the electron transport chain.

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