Nursing Elites

1. How can a single gene mutation lead to multiple phenotypes depending on the organism?

• A. Pleiotropy describes the effect of one gene influencing multiple seemingly unrelated traits.
• B. Epigenetics involves environmental factors modifying gene expression without altering the DNA sequence.
• C. Genetic drift refers to random changes in allele frequencies within a population.
• D. Gene regulation controls the timing and level of gene expression within an organism.

Correct answer: A

Rationale: A single gene mutation can lead to multiple phenotypes through pleiotropy, where one gene influences diverse traits or functions in an organism. This phenomenon occurs when the mutated gene affects different biochemical pathways, developmental processes, or cellular functions, resulting in a cascade of downstream effects that manifest as a variety of phenotypic outcomes. Choice B, epigenetics, involves modifications in gene expression influenced by environmental factors without altering the DNA sequence, which is not directly related to the question about single gene mutations causing multiple phenotypes. Choice C, genetic drift, refers to random changes in allele frequencies within a population, which is unrelated to the impact of a single gene mutation on multiple phenotypes. Choice D, gene regulation, focuses on controlling the timing and level of gene expression within an organism, which is not directly addressing how a single gene mutation can lead to diverse phenotypes.

2. Which of the following is the smallest unit of matter?

• A. Molecule
• B. Atom
• C. Compound
• D. Element

Correct answer: B

Rationale: An atom is the fundamental building block of matter, while molecules are formed by the combination of atoms.

3. Which of the following best describes the relationship among density, volume, and mass?

• A. As volume increases, density decreases.
• B. As volume decreases, density increases.
• C. An object's mass does not affect its density.
• D. As volume decreases, mass increases.

Correct answer: B

Rationale: The correct answer is B: 'As volume decreases, density increases.' This is because density is defined as mass divided by volume. When volume decreases and mass remains constant, the ratio of mass to volume increases, leading to higher density. Choice A is incorrect because as volume increases, density typically remains constant or increases due to the mass also increasing. Choice C is incorrect because an object's density is directly influenced by its mass. Choice D is incorrect as decreasing volume does not lead to an increase in mass.

4. What is the process of copying DNA called?

• A. Transcription
• B. Translation
• C. Replication
• D. Mutation

Correct answer: C

Rationale: The correct answer is C, Replication. Replication is the process of making an identical copy of DNA. During replication, the DNA double helix unwinds, and each strand serves as a template for the synthesis of a new complementary strand, resulting in two identical DNA molecules. Transcription (choice A) involves the synthesis of mRNA from a DNA template, not the direct copying of DNA. Translation (choice B) is the process of converting mRNA into a sequence of amino acids to form a protein, not copying DNA. Mutation (choice D) refers to changes in the DNA sequence, which can occur during replication but is not the process of copying DNA itself.

5. What term describes the functional unit of a skeletal muscle responsible for muscle contraction?

• A. Myofibril
• B. Sarcomere
• C. Tendon
• D. Myoglobin

Correct answer: B

Rationale: The correct answer is B, 'Sarcomere.' The sarcomere is indeed the functional unit of a skeletal muscle responsible for muscle contraction. It is composed of actin and myosin filaments that interact to generate muscle contraction. Choice A, 'Myofibril,' is incorrect as myofibrils are composed of sarcomeres, not the functional units themselves. Choice C, 'Tendon,' is incorrect as tendons connect muscles to bones and do not directly participate in muscle contraction. Choice D, 'Myoglobin,' is incorrect as myoglobin is a protein that stores oxygen in muscle cells and is not directly involved in muscle contraction.

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