Nursing Elites

1. How can a single gene mutation lead to multiple phenotypes depending on the organism?

• A. Pleiotropy describes the effect of one gene influencing multiple seemingly unrelated traits.
• B. Epigenetics involves environmental factors modifying gene expression without altering the DNA sequence.
• C. Genetic drift refers to random changes in allele frequencies within a population.
• D. Gene regulation controls the timing and level of gene expression within an organism.

Correct answer: A

Rationale: A single gene mutation can lead to multiple phenotypes through pleiotropy, where one gene influences diverse traits or functions in an organism. This phenomenon occurs when the mutated gene affects different biochemical pathways, developmental processes, or cellular functions, resulting in a cascade of downstream effects that manifest as a variety of phenotypic outcomes. Choice B, epigenetics, involves modifications in gene expression influenced by environmental factors without altering the DNA sequence, which is not directly related to the question about single gene mutations causing multiple phenotypes. Choice C, genetic drift, refers to random changes in allele frequencies within a population, which is unrelated to the impact of a single gene mutation on multiple phenotypes. Choice D, gene regulation, focuses on controlling the timing and level of gene expression within an organism, which is not directly addressing how a single gene mutation can lead to diverse phenotypes.

2. What is the name of the regulatory region in a gene that controls its expression?

• A. Exon
• B. Intron
• C. Promoter
• D. Enhancer

Correct answer: C

Rationale: A) Exon: Exons are the coding regions of a gene that are transcribed into mRNA and eventually translated into proteins. Exons do not regulate gene expression. B) Intron: Introns are non-coding regions of a gene that are removed during RNA processing and do not play a direct role in controlling gene expression. C) Promoter: The promoter is a regulatory region located at the beginning of a gene that initiates the process of transcription by binding transcription factors and RNA polymerase. It plays a crucial role in controlling gene expression. D) Enhancer: Enhancers are regulatory regions that can be located far from the gene they regulate and can increase the transcription of a gene. While enhancers are important for gene expression, the specific region that controls gene expression is the promoter. Therefore, the correct answer is C) Promoter, as it is the regulatory region in a gene that controls its expression by initiating transcription.

3. When a certain plant is introduced into an area, and the population of a certain insect species declines, what can be concluded from this?

• A. The plant is toxic to the insect in question.
• B. The plant competes with and drives out plants that the insect feeds on.
• C. The insect population was declining anyway; the fact that it happened when the plant was introduced is a coincidence.
• D. All of these explanations may be possible; further investigation is necessary to determine which is true.

Correct answer: D

Rationale: The given scenario presents multiple possible explanations for the decline in the insect population with the introduction of a particular plant. It could be due to the plant being toxic to the insect (Option A), competing with and driving out plants that the insect feeds on (Option B), or the decline could be coincidental with the plant introduction as the insect population was already decreasing (Option C). Without further investigation and evidence, it is not possible to definitively determine which explanation is correct. Therefore, all of these possibilities may be true, and thorough investigation is necessary to reach a conclusive conclusion.

4. What happens to the force of gravity between two objects when the distance between them is doubled?

• A. The force increases by a factor of 2
• B. The force increases by a factor of 4
• C. The force decreases by a factor of 2
• D. The force decreases by a factor of 4

Correct answer: D

Rationale: According to the law of universal gravitation, the force of gravity between two objects is inversely proportional to the square of the distance between them. When the distance is doubled, the force decreases by a factor of 2 squared, which is 4. Therefore, the force decreases by a factor of 4. Choice A is incorrect because the force doesn't increase when the distance is doubled. Choice B is incorrect as the force doesn't increase but actually decreases. Choice C is incorrect as the force decreases by a factor of 4, not 2.

5. Two mice are both heterozygous for two traits: white fur (Ww) and short fur (Ss). Their offspring are most likely to have which of the following genotypes for these traits?

• A. wwss
• B. WWSS
• C. WwSs
• D. WWSs

Correct answer: C

Rationale: When two mice that are heterozygous for white fur (Ww) and short fur (Ss) mate, they can produce offspring with different combinations of the two traits. The Punnett square for this cross shows that the most likely genotype for the offspring is WwSs. In this case, each offspring receives one allele for white fur (W) and one for short fur (S) from each parent, resulting in a heterozygous genotype for both traits. Choice A (wwss) is incorrect as it represents a homozygous recessive genotype for both traits. Choice B (WWSS) is also incorrect as it represents a homozygous dominant genotype for both traits. Choice D (WWSs) is incorrect as it represents a genotype where one trait is homozygous dominant (W) and the other is heterozygous (S), which is not the most likely outcome based on the given parental genotypes.

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