Nursing Elites

1. How can a single gene mutation lead to multiple phenotypes depending on the organism?

• A. Pleiotropy describes the effect of one gene influencing multiple seemingly unrelated traits.
• B. Epigenetics involves environmental factors modifying gene expression without altering the DNA sequence.
• C. Genetic drift refers to random changes in allele frequencies within a population.
• D. Gene regulation controls the timing and level of gene expression within an organism.

Correct answer: A

Rationale: A single gene mutation can lead to multiple phenotypes through pleiotropy, where one gene influences diverse traits or functions in an organism. This phenomenon occurs when the mutated gene affects different biochemical pathways, developmental processes, or cellular functions, resulting in a cascade of downstream effects that manifest as a variety of phenotypic outcomes. Choice B, epigenetics, involves modifications in gene expression influenced by environmental factors without altering the DNA sequence, which is not directly related to the question about single gene mutations causing multiple phenotypes. Choice C, genetic drift, refers to random changes in allele frequencies within a population, which is unrelated to the impact of a single gene mutation on multiple phenotypes. Choice D, gene regulation, focuses on controlling the timing and level of gene expression within an organism, which is not directly addressing how a single gene mutation can lead to diverse phenotypes.

2. What type of muscle is found in the walls of the heart?

• A. Smooth muscle
• B. Cardiac muscle
• C. Skeletal muscle
• D. Voluntary muscle

Correct answer: B

Rationale: The correct answer is B: Cardiac muscle. Cardiac muscle is the specialized muscle found in the walls of the heart. It contracts involuntarily to pump blood throughout the body, ensuring circulation. Smooth muscle is typically found in organs like the intestines and blood vessels, aiding in their functions. Skeletal muscle is attached to bones and plays a vital role in movement and posture. Voluntary muscle is a general term for skeletal muscles that are under conscious control, unlike cardiac muscle which contracts involuntarily to maintain the heart's continuous pumping action.

3. Differentiate between genotype and phenotype in the context of gene expression.

• A. Genotype refers to the physical manifestation of a trait, while phenotype represents its underlying genetic makeup.
• B. Genotype encompasses the spectrum of possible traits encoded by an organism's genes, while phenotype signifies the specific trait observed.
• C. Genotype denotes the presence of dominant alleles, while phenotype reflects the influence of recessive alleles.
• D. There is no distinction; both terms are interchangeable.

Correct answer: B

Rationale: - Genotype refers to the genetic makeup of an organism, including all the genes and alleles it possesses. - Phenotype, on the other hand, refers to the observable physical characteristics or traits of an organism, which result from the interaction between its genotype and the environment. - While genotype represents the genetic potential or range of traits that an organism can express, phenotype reflects the actual expression of specific traits. - Therefore, option B correctly captures the distinction between genotype and phenotype in the context of gene expression.

4. The average life expectancy at birth in the United States at the beginning of the 21st century was about 75 years. The average life expectancy at birth in the middle of the 19th century was only about 40 years. Which of the following factors are likely to have contributed to the longer life expectancy in the 21st century? (Select the one that does not apply)

• A. The human body has evolved to become more resilient to its environment.
• B. There have been numerous advances in medical technology and treatments.
• C. Higher standards of basic cleanliness have helped people avoid illness.
• D. The creation of vaccines has nearly eliminated certain diseases that were once deadly.

Correct answer: A

Rationale: Medical advances, higher standards of cleanliness, and the creation of vaccines have all significantly contributed to the increase in life expectancy over time. While human evolution plays a role in adaptation to the environment over millennia, it is not a primary factor that has led to the substantial increase in life expectancy within a few centuries. The human body's evolution is a slow process that occurs over generations, while the advancements in medical technology, cleanliness, and vaccines have had a more immediate and direct impact on improving life expectancy.

5. Which property of a wave remains constant when the wave enters a different medium?

• A. Frequency
• B. Wavelength
• C. Amplitude
• D. Speed

Correct answer: A

Rationale: When a wave enters a different medium, its frequency remains constant. Frequency is an intrinsic property of the wave determined by its source, and it does not change when transitioning between different mediums. On the other hand, wavelength, amplitude, and speed of the wave can all be altered when the wave moves from one medium to another. Wavelength is dependent on the speed of the wave and can change when entering a different medium due to differences in propagation speed. Amplitude can also change as it is influenced by factors like energy loss or gain at the boundary of the mediums. Speed, determined by the medium's properties, typically changes when a wave transitions between different mediums due to variations in the medium's density and elasticity.

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