Nursing Elites

1. What is a condition characterized by an overactive thyroid gland and excessive production of thyroid hormones called?

• A. Diabetes mellitus
• B. Hyperthyroidism
• C. Hypothyroidism
• D. Cushing's syndrome

Correct answer: B

Rationale: Hyperthyroidism is a condition where the thyroid gland is overactive and produces an excessive amount of thyroid hormones. This can lead to symptoms such as weight loss, rapid heartbeat, sweating, and nervousness. Diabetes mellitus is a condition characterized by high blood sugar levels due to either insufficient insulin production or the body's inability to respond to insulin. Hypothyroidism is the opposite of hyperthyroidism, where the thyroid gland is underactive and produces insufficient thyroid hormones. Cushing's syndrome is a disorder that occurs when the body has a high level of the hormone cortisol for a long time.

2. What is the role of the spindle apparatus in cell division?

• A. To separate sister chromatids
• B. To move chromosomes to opposite poles of the cell
• C. To form a new nuclear envelope around each daughter cell
• D. To synthesize new DNA

Correct answer: B

Rationale: The spindle apparatus, composed of microtubules, plays a crucial role in cell division (mitosis and meiosis) by ensuring proper chromosome separation and distribution to opposite poles of the cell. This segregation is vital for creating two genetically identical daughter cells in mitosis or four haploid daughter cells in meiosis. Choice A is incorrect because the separation of sister chromatids is specifically carried out by kinetochore fibers within the spindle apparatus. Choice C is inaccurate as the formation of a new nuclear envelope occurs post chromosome segregation. Choice D is incorrect as DNA synthesis does not occur within the spindle apparatus; it takes place during the S phase of the cell cycle.

3. Which of the following is an example of a fibrous protein?

• A. Insulin
• B. Keratin
• C. Hemoglobin
• D. Collagen

Correct answer: D

Rationale: A) Insulin is a hormone, not a fibrous protein. It is produced in the pancreas and regulates blood sugar levels. B) Keratin is a fibrous structural protein found in hair, nails, and the outer skin layer, providing strength and protection. C) Hemoglobin is a globular protein in red blood cells responsible for oxygen transport; it is not fibrous. D) Collagen is a fibrous protein found in tendons, ligaments, and skin, offering strength and structure to connective tissues. Therefore, the correct answer is collagen, making it the main component of various connective tissues.

4. Differentiate between gene therapy and genetic engineering in the context of human intervention.

• A. Gene therapy aims to modify existing genes within body cells, while genetic engineering manipulates genes in embryos to be passed on to offspring.
• B. Gene therapy focuses on treating genetic diseases, while genetic engineering enhances desirable traits or eliminates undesirable ones.
• C. Both involve directly altering the DNA sequence, but gene therapy targets somatic cells and genetic engineering modifies germline cells.
• D. There is no fundamental difference; both terms are synonymous.

Correct answer: B

Rationale: A) Incorrect. Gene therapy does aim to modify existing genes within body cells, but genetic engineering does not necessarily manipulate genes in embryos to be passed on to offspring. Genetic engineering can involve modifying genes in any type of cell, not just embryos. B) Correct. Gene therapy is a medical intervention that aims to treat genetic diseases by correcting or replacing faulty genes within an individual's body cells. On the other hand, genetic engineering involves modifying genes to enhance specific traits or eliminate undesirable ones, often in the context of agriculture or biotechnology. C) Incorrect. While both gene therapy and genetic engineering involve altering DNA sequences, the distinction lies in the target cells. Gene therapy targets somatic cells (non-reproductive cells), while genetic engineering typically involves modifying germline cells (reproductive cells that can pass on genetic changes to offspring). D) Incorrect. There is

5. Why is the lining of the stomach covered with rugae?

• A. Rugae increase the output of gastric juices.
• B. Rugae increase the surface area of the stomach.
• C. Rugae increase the permeability of the stomach walls.
• D. Rugae increase the types of nutrients that can diffuse.

Correct answer: B

Rationale: Rugae are folds in the stomach lining that increase its surface area. This increased surface area allows for more efficient digestion and absorption of nutrients in the stomach. Choice A is incorrect because rugae do not directly affect the output of gastric juices. Choice C is incorrect because rugae do not impact the permeability of the stomach walls. Choice D is incorrect because rugae do not influence the types of nutrients that can diffuse.

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