HESI RN
Biology Test
1. Which of the following statements is most accurate regarding the transcription of DNA?
- A. RNA uses reverse transcriptase to make mRNA
- B. DNA uses mRNA to produce tRNA
- C. RNA creates a duplicate copy of DNA
- D. RNA copies DNA to produce mRNA
Correct answer: D
Rationale: The correct answer is D. During transcription, RNA copies DNA to produce mRNA, which carries the genetic information from DNA to the ribosomes for protein synthesis. Choice A is incorrect because reverse transcriptase is not involved in the transcription of DNA. Choice B is incorrect as DNA does not use mRNA to produce tRNA; tRNA is produced through a different process. Choice C is incorrect as RNA does not create a duplicate copy of DNA during transcription; it synthesizes mRNA by copying the DNA template.
2. During cellular respiration, glycolysis takes place in the cytosol and produces how many molecules of ATP, pyruvate, and NADH?
- A. two, two, two
- B. two, four, two
- C. two, four, four
- D. four, four, four
Correct answer: A
Rationale: Glycolysis, the first step of cellular respiration, takes place in the cytosol and produces two molecules each of ATP, pyruvate, and NADH. Therefore, the correct answer is A. Choice B is incorrect as glycolysis produces two ATP molecules, not four. Choice C is incorrect as it incorrectly states that glycolysis produces four molecules of pyruvate and NADH. Choice D is incorrect because glycolysis produces two molecules of ATP, not four.
3. Protein synthesis begins with a process known as transcription. What is produced during this process?
- A. A codon
- B. A DNA helix
- C. A DNA strand
- D. An RNA strand
Correct answer: D
Rationale: The correct answer is D: An RNA strand. During transcription, the DNA template is used to produce an RNA strand, not a codon, DNA helix, or another DNA strand. A codon is a sequence of nucleotides that specifies a particular amino acid during translation, not produced during transcription. A DNA helix refers to the double-stranded structure of DNA, which is not produced during transcription. Another DNA strand is not produced during transcription since the process involves creating an RNA copy of a specific gene.
4. In meiosis, the chromosome number is reduced from:
- A. 46 to 23
- B. 46 to 33
- C. 28 to 14
- D. 24 to 12
Correct answer: A
Rationale: The correct answer is A: "46 to 23." In meiosis, the chromosome number is reduced by half to form gametes for sexual reproduction. In humans, where the diploid chromosome number is 46, meiosis results in haploid cells with 23 chromosomes. Choices B, C, and D are incorrect because they do not represent the correct reduction in chromosome number during meiosis.
5. In which step of cellular respiration is the most adenosine triphosphate (ATP) created?
- A. Electron transport chain
- B. Glycolysis
- C. Citric acid cycle (the Krebs cycle)
- D. All of these produce equal amounts of ATP
Correct answer: A
Rationale: The electron transport chain is the step in cellular respiration that generates the most ATP. During this step, up to 34 ATP molecules can be produced from a single glucose molecule. Choice B, Glycolysis, produces a smaller amount of ATP (2 ATP molecules per glucose), and choice C, Citric acid cycle, produces some ATP but not as much as the electron transport chain. Choice D is incorrect because different steps of cellular respiration produce varying amounts of ATP, with the electron transport chain being the most efficient in ATP generation.
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