HESI RN
Biology Test
1. Which of the following statements is most accurate regarding the transcription of DNA?
- A. RNA uses reverse transcriptase to make mRNA
- B. DNA uses mRNA to produce tRNA
- C. RNA creates a duplicate copy of DNA
- D. RNA copies DNA to produce mRNA
Correct answer: D
Rationale: The correct answer is D. During transcription, RNA copies DNA to produce mRNA, which carries the genetic information from DNA to the ribosomes for protein synthesis. Choice A is incorrect because reverse transcriptase is not involved in the transcription of DNA. Choice B is incorrect as DNA does not use mRNA to produce tRNA; tRNA is produced through a different process. Choice C is incorrect as RNA does not create a duplicate copy of DNA during transcription; it synthesizes mRNA by copying the DNA template.
2. What is the most significant contributor to cellular function?
- A. Proteins
- B. Phospholipids
- C. Carbohydrates
- D. Fatty acids
Correct answer: A
Rationale: The correct answer is A: Proteins. Proteins are the most significant contributor to cellular function as they play crucial roles in almost all biological processes. They act as enzymes that catalyze reactions, are involved in cell signaling pathways, and provide structural support to cells. Phospholipids (Choice B), while important for cell membrane structure, do not have the same diverse functions as proteins in cellular processes. Carbohydrates (Choice C) primarily serve as an energy source and structural components but are not as versatile in cellular functions as proteins. Fatty acids (Choice D) are essential components of cell membranes and energy storage molecules but do not have the same broad range of functions as proteins in cellular processes.
3. The liver is an organ responsible for detoxifying the body of many harmful substances. You might expect the liver to contain a high amount of which of the following?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B: Smooth endoplasmic reticulum. The liver contains a high amount of smooth endoplasmic reticulum because it plays a significant role in detoxification processes, such as the synthesis of detoxifying enzymes and lipids. Choice A (Rough endoplasmic reticulum) is incorrect because the rough endoplasmic reticulum is more involved in protein synthesis and processing. Choice C (Mitochondria) is incorrect as mitochondria are primarily responsible for energy production. Choice D (Lysosomes) is incorrect because lysosomes are organelles involved in intracellular digestion and waste removal, not specifically related to detoxification.
4. The term pleiotropy is best defined as which of the following?
- A. A situation in which one gene remains unexpressed
- B. One gene influencing multiple, seemingly unrelated phenotypic traits
- C. Two genes affected by a single allele
- D. A condition in which multiple genes are missing
Correct answer: B
Rationale: Pleiotropy is best defined as one gene influencing multiple, seemingly unrelated phenotypic traits. This phenomenon showcases the multifunctionality of genes, where a single gene can have effects on various aspects of an organism's phenotype. Choices A, C, and D do not accurately capture the concept of pleiotropy. Option A refers to gene expression, not pleiotropy. Option C describes genetic interactions but not in the context of pleiotropy. Option D talks about missing genes, which is unrelated to the definition of pleiotropy.
5. In which step of cellular respiration is the most adenosine triphosphate (ATP) created?
- A. Electron transport chain
- B. Glycolysis
- C. Citric acid cycle (the Krebs cycle)
- D. All of these produce equal amounts of ATP
Correct answer: A
Rationale: The electron transport chain is the step in cellular respiration that generates the most ATP. During this step, up to 34 ATP molecules can be produced from a single glucose molecule. Choice B, Glycolysis, produces a smaller amount of ATP (2 ATP molecules per glucose), and choice C, Citric acid cycle, produces some ATP but not as much as the electron transport chain. Choice D is incorrect because different steps of cellular respiration produce varying amounts of ATP, with the electron transport chain being the most efficient in ATP generation.
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