HESI RN
Biology Practice Test
1. In the hierarchy of biology, cells combine to form which of the following?
- A. Macromolecules
- B. Molecules
- C. Tissues
- D. Organelles
Correct answer: C
Rationale: In the hierarchy of biology, cells combine to form tissues. Tissues are groups of cells that work together to perform specific functions. This is a fundamental level of organization above individual cells but below organs and organ systems. Macromolecules and molecules are smaller components that make up cells, not what cells combine to form. Organelles are structures within cells that perform specific functions and do not result from the combination of cells.
2. Protein synthesis begins with a process known as transcription. What is produced during this process?
- A. A codon
- B. A DNA helix
- C. A DNA strand
- D. An RNA strand
Correct answer: D
Rationale: The correct answer is D: An RNA strand. During transcription, the DNA template is used to produce an RNA strand, not a codon, DNA helix, or another DNA strand. A codon is a sequence of nucleotides that specifies a particular amino acid during translation, not produced during transcription. A DNA helix refers to the double-stranded structure of DNA, which is not produced during transcription. Another DNA strand is not produced during transcription since the process involves creating an RNA copy of a specific gene.
3. Which of the following molecules acts as the genetic code's messenger?
- A. RNA
- B. Proteins
- C. DNA
- D. Carbohydrates
Correct answer: A
Rationale: The correct answer is RNA. RNA, particularly mRNA, serves as the messenger that carries genetic information from DNA to the ribosome, where proteins are synthesized. Proteins (choice B) are not the genetic code's messenger; they are synthesized based on the information carried by RNA. DNA (choice C) stores the genetic information but does not directly act as the messenger. Carbohydrates (choice D) are not involved in transmitting genetic information.
4. Which of the following statements is most accurate regarding the transcription of DNA?
- A. RNA uses reverse transcriptase to make mRNA
- B. DNA uses mRNA to produce tRNA
- C. RNA creates a duplicate copy of DNA
- D. RNA copies DNA to produce mRNA
Correct answer: D
Rationale: The correct answer is D. During transcription, RNA copies DNA to produce mRNA, which carries the genetic information from DNA to the ribosomes for protein synthesis. Choice A is incorrect because reverse transcriptase is not involved in the transcription of DNA. Choice B is incorrect as DNA does not use mRNA to produce tRNA; tRNA is produced through a different process. Choice C is incorrect as RNA does not create a duplicate copy of DNA during transcription; it synthesizes mRNA by copying the DNA template.
5. Which of the following processes produces nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FADH2) for the electron transport chain during cellular respiration?
- A. Electron transport chain
- B. Glycolysis
- C. Citric acid cycle (the Krebs cycle)
- D. None of these
Correct answer: C
Rationale: The correct answer is C, the citric acid cycle (the Krebs cycle). This cycle generates NADH and FADH2, which play a crucial role in providing electrons to the electron transport chain during cellular respiration. Choice A, the electron transport chain itself, is where NADH and FADH2 donate their electrons, not where they are produced. Choice B, glycolysis, produces NADH but not FADH2. Choice D, 'None of these,' is incorrect as the citric acid cycle specifically produces NADH and FADH2.
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