HESI RN
Biology Practice Test
1. The Punnett square shows that one parent carries the recessive gene for a cleft chin (c) while the other parent does not. What percentage of the parents' offspring is predicted to have a cleft chin?
- A. 25%
- B. 50%
- C. 0%
- D. 75%
Correct answer: C
Rationale: The correct answer is 0%. If one parent carries the recessive gene for a cleft chin while the other parent does not, none of the offspring will express the recessive phenotype. This is because in order for a child to have a cleft chin, they would need to inherit the recessive gene from both parents. Therefore, although the offspring could be carriers of the gene, none are predicted to have a cleft chin. Choices A, B, and D are incorrect because the presence of the recessive gene in one parent and its absence in the other would not result in any offspring showing the cleft chin trait.
2. Which of the following molecules contains the code required for replication?
- A. Deoxyribonucleic acid (DNA)
- B. Transfer RNA (tRNA)
- C. Messenger RNA (mRNA)
- D. Ribonucleic acid (RNA)
Correct answer: A
Rationale: The correct answer is A: Deoxyribonucleic acid (DNA). DNA contains the genetic information essential for replication, ensuring the accurate transmission of genetic material from one generation to the next. Choice B, Transfer RNA (tRNA), is involved in protein synthesis, not replication. Choice C, Messenger RNA (mRNA), carries genetic information from DNA to the ribosome but does not contain the code for replication. Choice D, Ribonucleic acid (RNA), is a broader category that includes both mRNA and tRNA, but the specific molecule containing the code required for replication is DNA.
3. What is located on the rough endoplasmic reticulum?
- A. Microvilli
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: D
Rationale: The rough endoplasmic reticulum is studded with ribosomes, which are responsible for protein synthesis. Ribosomes are the correct answer because they are the organelles directly associated with the rough endoplasmic reticulum. Microvilli (choice A), mitochondria (choice B), and lysosomes (choice C) are not typically located on the rough endoplasmic reticulum. Microvilli are found on the surface of cells to increase surface area, mitochondria are the powerhouses of the cell responsible for energy production, and lysosomes are membrane-bound organelles containing digestive enzymes.
4. Which of the following is responsible for the synthesis of carbohydrates, lipids, and steroid hormones?
- A. Smooth endoplasmic reticulum (ER)
- B. Rough endoplasmic reticulum (ER)
- C. Golgi apparatus
- D. Ribosomes
Correct answer: A
Rationale: The smooth endoplasmic reticulum (ER) is the correct answer. It is responsible for the synthesis of lipids, including steroids, and also plays a role in carbohydrate metabolism. The rough endoplasmic reticulum (ER) is involved in protein synthesis and processing, not lipid or carbohydrate synthesis. The Golgi apparatus is responsible for modifying, sorting, and packaging of proteins and lipids, but not for their synthesis. Ribosomes are the cellular organelles responsible for protein synthesis, not lipid or carbohydrate synthesis.
5. Which of the following organelles is known as the cell's digestion center?
- A. Chloroplasts
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C: Lysosomes. Lysosomes contain enzymes that break down waste materials and cellular debris within the cell, making them the cell's digestion center. Choice A, Chloroplasts, are responsible for photosynthesis. Choice B, Mitochondria, are the powerhouse of the cell, generating energy. Choice D, Ribosomes, are involved in protein synthesis. Therefore, Lysosomes are specifically known for their role in digestion within the cell.
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