HESI RN
Biology Test
1. Which of the following molecules acts as the genetic code's messenger?
- A. RNA
- B. Proteins
- C. DNA
- D. Carbohydrates
Correct answer: A
Rationale: The correct answer is RNA. RNA, particularly mRNA, serves as the messenger that carries genetic information from DNA to the ribosome, where proteins are synthesized. Proteins (choice B) are not the genetic code's messenger; they are synthesized based on the information carried by RNA. DNA (choice C) stores the genetic information but does not directly act as the messenger. Carbohydrates (choice D) are not involved in transmitting genetic information.
2. In DNA, the nucleotide base adenine always binds with which of the following?
- A. Guanine
- B. Uracil
- C. Thymine
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Thymine. In DNA, adenine always pairs with thymine, forming a base pair held together by hydrogen bonds. Guanine pairs with cytosine. Uracil is found in RNA, not DNA. Cytosine pairs with guanine. Therefore, option C is the correct pairing for adenine in DNA.
3. During cellular respiration, glycolysis takes place in the cytosol and produces how many molecules of ATP, pyruvate, and NADH?
- A. two, two, two
- B. two, four, two
- C. two, four, four
- D. four, four, four
Correct answer: A
Rationale: Glycolysis, the first step of cellular respiration, takes place in the cytosol and produces two molecules each of ATP, pyruvate, and NADH. Therefore, the correct answer is A. Choice B is incorrect as glycolysis produces two ATP molecules, not four. Choice C is incorrect as it incorrectly states that glycolysis produces four molecules of pyruvate and NADH. Choice D is incorrect because glycolysis produces two molecules of ATP, not four.
4. Which cell structure is responsible for efficiently packaging DNA into a small volume to fit into the nucleus of a cell and protect the DNA structure and sequence?
- A. Golgi apparatus
- B. Chromatin
- C. Smooth endoplasmic reticulum
- D. Mitochondria
Correct answer: B
Rationale: The correct answer is B: Chromatin. Chromatin is responsible for packaging DNA into a more compact, dense shape to fit into the nucleus of a cell. This compact packaging helps protect the DNA structure and regulate gene expression. The Golgi apparatus is involved in modifying, sorting, and packaging proteins. The smooth endoplasmic reticulum is involved in lipid metabolism and detoxification. Mitochondria are known as the powerhouse of the cell, producing energy in the form of ATP.
5. Which of the following is not found in a prokaryotic cell?
- A. Plasma membrane
- B. Cytoplasm
- C. Nucleus
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C, 'Nucleus.' Prokaryotic cells do not have a defined nucleus, unlike eukaryotic cells. The plasma membrane, cytoplasm, and ribosomes are all components found in prokaryotic cells. The plasma membrane surrounds the cell and regulates what enters and exits, the cytoplasm is the gel-like substance that fills the cell, and ribosomes are responsible for protein synthesis.
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