HESI RN
Biology Test
1. During which stage of mitosis does the nuclear envelope begin to disappear and the chromosomes start attaching to the spindle forming along the cell's axis?
- A. Prometaphase
- B. Metaphase
- C. Anaphase
- D. Prophase
Correct answer: A
Rationale: The correct answer is A, Prometaphase. During prometaphase, the nuclear envelope disintegrates, and chromosomes start attaching to spindle fibers. In metaphase, chromosomes align in the middle of the cell. Anaphase is characterized by the separation of sister chromatids, and prophase involves the condensation of chromosomes and the beginning of spindle formation.
2. Which of the following is the process that reduces cells originally classified as diploid to haploid?
- A. Meiosis
- B. Photosynthesis
- C. Mitosis
- D. Cytokinesis
Correct answer: A
Rationale: The correct answer is A, Meiosis. Meiosis is the cell division process that reduces the chromosome number from diploid to haploid, which is essential for sexual reproduction. Choice B, Photosynthesis, is the process by which green plants and some other organisms use sunlight to synthesize foods with the help of chlorophyll. Choice C, Mitosis, is a cell division process that results in two diploid daughter cells with the same number of chromosomes as the parent cell. Choice D, Cytokinesis, is the division of the cytoplasm following cell division.
3. Which organelle has the ability to hydrolyze fats, nucleic acids, proteins, and sugars?
- A. Chloroplasts
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C, Lysosomes. Lysosomes contain hydrolytic enzymes that are capable of breaking down various biomolecules such as fats, nucleic acids, proteins, and sugars. This organelle acts as the 'digestive system' of the cell. Choices A, B, and D are incorrect because chloroplasts are involved in photosynthesis, mitochondria are responsible for energy production, and ribosomes are responsible for protein synthesis, not the hydrolysis of biomolecules.
4. What percentage of the parents' offspring is predicted to have a cleft chin if one parent carries the recessive gene for a cleft chin (c) while the other parent does not?
- A. 25%
- B. 50%
- C. 0%
- D. 75%
Correct answer: C
Rationale: The correct answer is C (0%). If one parent carries the recessive gene for a cleft chin while the other parent does not carry it, none of their offspring is predicted to have a cleft chin. This is because the cleft chin trait is recessive, so for an offspring to express this trait, they would need to inherit the gene from both parents. In this scenario, none of the offspring will inherit the recessive gene from both parents, so the percentage of offspring predicted to have a cleft chin is 0%. Choices A, B, and D are incorrect because in this situation, the offspring will not express the cleft chin phenotype, although they could be carriers of the recessive gene.
5. What is considered the main objective of the translation stage of protein synthesis?
- A. To produce amino acids
- B. To produce nucleotides
- C. To produce fatty acids
- D. To produce nucleic acids
Correct answer: A
Rationale: The correct answer is A: To produce amino acids. During the translation stage of protein synthesis, the mRNA is decoded to assemble a specific sequence of amino acids. These amino acids then fold into a functional protein. Choices B, C, and D are incorrect because the translation stage specifically deals with the production of amino acids, not nucleotides, fatty acids, or nucleic acids.
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