HESI RN
Biology Practice Test
1. What is located on the rough endoplasmic reticulum?
- A. Microvilli
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: D
Rationale: The rough endoplasmic reticulum is studded with ribosomes, which are responsible for protein synthesis. Ribosomes are the correct answer because they are the organelles directly associated with the rough endoplasmic reticulum. Microvilli (choice A), mitochondria (choice B), and lysosomes (choice C) are not typically located on the rough endoplasmic reticulum. Microvilli are found on the surface of cells to increase surface area, mitochondria are the powerhouses of the cell responsible for energy production, and lysosomes are membrane-bound organelles containing digestive enzymes.
2. The cellular membrane contributes to all except which of the following?
- A. Cell energy production
- B. Cell permeability
- C. Cell communication
- D. Cell protection
Correct answer: A
Rationale: The cellular membrane is involved in regulating cell permeability, communication, and protection. However, it is not directly involved in energy production. Choice A is the correct answer because the cellular membrane does not produce energy; instead, it regulates the passage of molecules in and out of the cell. Choices B, C, and D are incorrect because the cell membrane plays key roles in controlling what enters and exits the cell, facilitating communication between cells, and providing structural support and protection to the cell.
3. Which of the following processes produces nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FADH2) for the electron transport chain during cellular respiration?
- A. Electron transport chain
- B. Glycolysis
- C. Citric acid cycle (the Krebs cycle)
- D. None of these
Correct answer: C
Rationale: The correct answer is C, the citric acid cycle (the Krebs cycle). This cycle generates NADH and FADH2, which play a crucial role in providing electrons to the electron transport chain during cellular respiration. Choice A, the electron transport chain itself, is where NADH and FADH2 donate their electrons, not where they are produced. Choice B, glycolysis, produces NADH but not FADH2. Choice D, 'None of these,' is incorrect as the citric acid cycle specifically produces NADH and FADH2.
4. Which organelle has the ability to hydrolyze fats, nucleic acids, proteins, and sugars?
- A. Chloroplasts
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C, Lysosomes. Lysosomes contain hydrolytic enzymes that are capable of breaking down various biomolecules such as fats, nucleic acids, proteins, and sugars. This organelle acts as the 'digestive system' of the cell. Choices A, B, and D are incorrect because chloroplasts are involved in photosynthesis, mitochondria are responsible for energy production, and ribosomes are responsible for protein synthesis, not the hydrolysis of biomolecules.
5. In DNA, the nucleotide base adenine always binds with which of the following?
- A. Guanine
- B. Uracil
- C. Thymine
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Thymine. In DNA, adenine always pairs with thymine, forming a base pair held together by hydrogen bonds. Guanine pairs with cytosine. Uracil is found in RNA, not DNA. Cytosine pairs with guanine. Therefore, option C is the correct pairing for adenine in DNA.
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