HESI RN
Biology Test
1. What cell structure is responsible for efficiently packaging DNA into a small volume to fit into the nucleus of a cell and protect the DNA structure and sequence?
- A. Golgi apparatus
- B. Chromatin
- C. Smooth endoplasmic reticulum
- D. Mitochondria
Correct answer: B
Rationale: Chromatin is the correct answer. Chromatin is responsible for packaging DNA into a more compact, dense structure to fit into the nucleus and protect the DNA. The Golgi apparatus is involved in processing and packaging proteins, not DNA. Smooth endoplasmic reticulum is involved in lipid metabolism and detoxification. Mitochondria are known as the powerhouse of the cell responsible for energy production, not DNA packaging.
2. In DNA, the nucleotide base adenine always binds with which of the following?
- A. Guanine
- B. Uracil
- C. Thymine
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Thymine. In DNA, adenine always pairs with thymine, forming a base pair held together by hydrogen bonds. Guanine pairs with cytosine. Uracil is found in RNA, not DNA. Cytosine pairs with guanine. Therefore, option C is the correct pairing for adenine in DNA.
3. Where can ribosomes be found inside a cell?
- A. Attached to the endoplasmic reticulum (ER) and in the cytoplasm
- B. Within the cellular membrane
- C. Attached to the Golgi apparatus and in the cytoplasm
- D. Within the nucleus
Correct answer: A
Rationale: Ribosomes can be found attached to the endoplasmic reticulum (ER) or free-floating in the cytoplasm. The correct answer is A because ribosomes are responsible for synthesizing proteins and are commonly found on the ER or in the cytoplasm. Choice B is incorrect because ribosomes are not typically located within the cellular membrane. Choice C is incorrect as ribosomes are not attached to the Golgi apparatus; instead, they are involved in protein synthesis. Choice D is incorrect as ribosomes are not found within the nucleus but rather in the cytoplasm or attached to the ER.
4. A water molecule contains two types of atoms that are covalently bonded. Which of the following makes up a water molecule?
- A. One hydrogen atom and one oxygen atom
- B. One hydrogen atom and two oxygen atoms
- C. Two hydrogen atoms and two oxygen atoms
- D. Two hydrogen atoms and one oxygen atom
Correct answer: D
Rationale: The correct answer is D: Two hydrogen atoms and one oxygen atom. A water molecule consists of two hydrogen atoms covalently bonded to one oxygen atom. This forms a stable structure known as H2O. Choice A is incorrect as water molecule contains two hydrogen atoms. Choices B and C are incorrect as they do not reflect the correct composition of a water molecule.
5. The bilayer of the cellular membrane consists of phospholipids with all except which of the following scattered throughout?
- A. Nucleic acids
- B. Cholesterol
- C. Proteins
- D. Glycoproteins
Correct answer: A
Rationale: The cellular membrane is composed of a phospholipid bilayer with cholesterol, proteins, and glycoproteins distributed throughout. Nucleic acids are not found within the cellular membrane. Cholesterol helps maintain membrane fluidity, while proteins and glycoproteins play important roles in cell signaling, transport, and structural support.
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