HESI RN
Biology Practice Test
1. Where can ribosomes be found inside a cell?
- A. Attached to the endoplasmic reticulum (ER) and in the cytoplasm
- B. Within the cellular membrane
- C. Attached to the Golgi apparatus and in the cytoplasm
- D. Within the nucleus
Correct answer: A
Rationale: Ribosomes can be found attached to the endoplasmic reticulum (ER) or free-floating in the cytoplasm. The correct answer is A because ribosomes are responsible for synthesizing proteins and are commonly found on the ER or in the cytoplasm. Choice B is incorrect because ribosomes are not typically located within the cellular membrane. Choice C is incorrect as ribosomes are not attached to the Golgi apparatus; instead, they are involved in protein synthesis. Choice D is incorrect as ribosomes are not found within the nucleus but rather in the cytoplasm or attached to the ER.
2. During which stage of mitosis does the nuclear envelope begin to disappear and the chromosomes start attaching to the spindle forming along the cell's axis?
- A. Prometaphase
- B. Metaphase
- C. Anaphase
- D. Prophase
Correct answer: A
Rationale: The correct answer is A, Prometaphase. During prometaphase, the nuclear envelope disintegrates, and chromosomes start attaching to spindle fibers. In metaphase, chromosomes align in the middle of the cell. Anaphase is characterized by the separation of sister chromatids, and prophase involves the condensation of chromosomes and the beginning of spindle formation.
3. In meiosis, the chromosome number is reduced from:
- A. 46 to 23
- B. 46 to 33
- C. 28 to 14
- D. 24 to 12
Correct answer: A
Rationale: The correct answer is A: "46 to 23." In meiosis, the chromosome number is reduced by half to form gametes for sexual reproduction. In humans, where the diploid chromosome number is 46, meiosis results in haploid cells with 23 chromosomes. Choices B, C, and D are incorrect because they do not represent the correct reduction in chromosome number during meiosis.
4. Which of the following organelles is known as the cell's transportation center?
- A. Golgi apparatus
- B. Endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B, Endoplasmic reticulum. The endoplasmic reticulum is involved in the synthesis and transport of proteins and lipids within the cell. The Golgi apparatus is responsible for modifying, sorting, and packaging proteins and lipids for transport. Mitochondria are known as the powerhouse of the cell, producing energy in the form of ATP. Lysosomes are involved in the digestion and recycling of cellular waste.
5. Which of the following processes produces nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FADH2) for the electron transport chain during cellular respiration?
- A. Electron transport chain
- B. Glycolysis
- C. Citric acid cycle (the Krebs cycle)
- D. None of these
Correct answer: C
Rationale: The correct answer is C, the citric acid cycle (the Krebs cycle). This cycle generates NADH and FADH2, which play a crucial role in providing electrons to the electron transport chain during cellular respiration. Choice A, the electron transport chain itself, is where NADH and FADH2 donate their electrons, not where they are produced. Choice B, glycolysis, produces NADH but not FADH2. Choice D, 'None of these,' is incorrect as the citric acid cycle specifically produces NADH and FADH2.
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