HESI RN
Biology Test
1. What is the smallest and most basic unit of matter?
- A. Micromolecule
- B. Atom
- C. Organelle
- D. Molecule
Correct answer: B
Rationale: The correct answer is B, Atom. An atom is the smallest unit of matter that retains the properties of an element. Choice A, Micromolecule, is incorrect because molecules are composed of atoms bonded together, making them larger than individual atoms. Choice C, Organelle, is incorrect as organelles are structures within cells, not the basic unit of matter. Choice D, Molecule, is incorrect as molecules are made up of atoms bonded together, so they are not the smallest unit of matter.
2. What must first occur before a cell can be divided to grow, develop, and reproduce organisms?
- A. RNA replication
- B. DNA replication
- C. Gene replication
- D. Chromosome replication
Correct answer: B
Rationale: The correct answer is B: DNA replication. Before a cell can divide to grow, develop, and reproduce organisms, DNA replication must occur. This process ensures that each daughter cell receives an identical set of genetic information. Choices A, C, and D are incorrect because while RNA, genes, and chromosomes are essential components of cell division, DNA replication is the specific process that must first occur to ensure accurate transmission of genetic material.
3. Binary fission is a type of asexual reproduction. Which of the following occurs during the binary fission process?
- A. The chromosomes bind to the plasma membrane
- B. The chromosomes attach to the spindle formed along the axis
- C. The chromosomes gather in the center of the cell
- D. The chromosomes begin to separate
Correct answer: A
Rationale: The correct answer is A. In binary fission, the chromosomes bind to the plasma membrane before the cell splits into two. This initial step ensures that each daughter cell receives a complete set of genetic material. Choice B is incorrect because the spindle apparatus is characteristic of eukaryotic cell division (mitosis), not prokaryotic binary fission. Choice C is incorrect as chromosomes do not necessarily gather in the center of the cell during binary fission. Choice D is incorrect because the chromosomes do not begin to separate in binary fission; they replicate and then move to opposite ends of the cell before division.
4. What is the composition of the cellular membrane?
- A. A bilayer of phospholipid molecules
- B. A single layer of phospholipid molecules
- C. Proteins that act as transport highways
- D. Carbohydrates
Correct answer: A
Rationale: The cellular membrane is primarily composed of a phospholipid bilayer, which consists of two layers of phospholipid molecules. These molecules have a hydrophilic (water-attracting) head and hydrophobic (water-repelling) tail, creating a barrier that separates the internal cellular environment from the external surroundings. While proteins are embedded within this bilayer and act as transport channels, receptors, and structural support, carbohydrates are found on the outer surface of the membrane for cell recognition and signaling purposes. Therefore, the correct answer is a bilayer of phospholipid molecules.
5. In the hierarchical organizational system, which of these is the most restrictive category?
- A. Genus
- B. Class
- C. Kingdom
- D. Species
Correct answer: D
Rationale: In the biological classification hierarchy, species is the most specific level, defining individual organisms that can interbreed. While genus, class, and kingdom are also categories in the hierarchy, they are broader and encompass a wider range of organisms compared to species. Genus groups together similar species, class groups similar orders, and kingdom is the broadest category grouping together similar phyla.
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