HESI RN
Biology Practice Test
1. The liver is an organ responsible for detoxifying the body of many harmful substances. You might expect the liver to contain a high amount of which of the following?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B: Smooth endoplasmic reticulum. The liver contains a high amount of smooth endoplasmic reticulum because it plays a significant role in detoxification processes, such as the synthesis of detoxifying enzymes and lipids. Choice A (Rough endoplasmic reticulum) is incorrect because the rough endoplasmic reticulum is more involved in protein synthesis and processing. Choice C (Mitochondria) is incorrect as mitochondria are primarily responsible for energy production. Choice D (Lysosomes) is incorrect because lysosomes are organelles involved in intracellular digestion and waste removal, not specifically related to detoxification.
2. Where can ribosomes be found inside a cell?
- A. Attached to the endoplasmic reticulum (ER) and in the cytoplasm
- B. Within the cellular membrane
- C. Attached to the Golgi apparatus and in the cytoplasm
- D. Within the nucleus
Correct answer: A
Rationale: Ribosomes can be found attached to the endoplasmic reticulum (ER) or free-floating in the cytoplasm. The correct answer is A because ribosomes are responsible for synthesizing proteins and are commonly found on the ER or in the cytoplasm. Choice B is incorrect because ribosomes are not typically located within the cellular membrane. Choice C is incorrect as ribosomes are not attached to the Golgi apparatus; instead, they are involved in protein synthesis. Choice D is incorrect as ribosomes are not found within the nucleus but rather in the cytoplasm or attached to the ER.
3. Which of the following options correctly lists the five stages of mitosis in order from beginning to end?
- A. Prophase, Prometaphase, Telophase, Metaphase, Anaphase
- B. Prophase, Prometaphase, Metaphase, Anaphase, Telophase
- C. Metaphase, Anaphase, Prophase, Prometaphase, Telophase
- D. Metaphase, Telophase, Anaphase, Prophase, Prometaphase
Correct answer: B
Rationale: The correct order of the stages of mitosis is Prophase, Prometaphase, Metaphase, Anaphase, and Telophase. Choice A is incorrect because it has Anaphase and Metaphase in the wrong order. Choice C is incorrect as it starts with Metaphase, which is not the first stage of mitosis. Choice D is incorrect as it also has the stages in the wrong order, and it starts with Metaphase, which is incorrect.
4. Which of the following molecules contains the code required for replication?
- A. Deoxyribonucleic acid (DNA)
- B. Transfer RNA (tRNA)
- C. Messenger RNA (mRNA)
- D. Ribonucleic acid (RNA)
Correct answer: A
Rationale: The correct answer is A: Deoxyribonucleic acid (DNA). DNA contains the genetic information essential for replication, ensuring the accurate transmission of genetic material from one generation to the next. Choice B, Transfer RNA (tRNA), is involved in protein synthesis, not replication. Choice C, Messenger RNA (mRNA), carries genetic information from DNA to the ribosome but does not contain the code for replication. Choice D, Ribonucleic acid (RNA), is a broader category that includes both mRNA and tRNA, but the specific molecule containing the code required for replication is DNA.
5. Which of the following best describes phenotype?
- A. The hereditary potentials and limitations of an individual
- B. The genetic makeup of an individual organism
- C. The entire complex of genes inherited from both parents
- D. All the observable characteristics of an organism
Correct answer: D
Rationale: The correct answer is D: 'All the observable characteristics of an organism.' Phenotype refers to all the observable characteristics of an organism, such as physical appearance, behavior, and other traits, which result from the interaction of its genotype with the environment. Choice A is incorrect because it describes genotype. Choice B is incorrect as it defines genotype, not phenotype. Choice C is incorrect as it refers to the genotype, the genetic information inherited from both parents, rather than the observable traits.
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