HESI RN
Biology Practice Test
1. What is considered the main objective of the translation stage of protein synthesis?
- A. To produce amino acids
- B. To produce nucleotides
- C. To produce fatty acids
- D. To produce nucleic acids
Correct answer: A
Rationale: The correct answer is A: To produce amino acids. During the translation stage of protein synthesis, the mRNA is decoded to assemble a specific sequence of amino acids. These amino acids then fold into a functional protein. Choices B, C, and D are incorrect because the translation stage specifically deals with the production of amino acids, not nucleotides, fatty acids, or nucleic acids.
2. Which of the following is a group of three RNA nucleotides?
- A. A stop codon
- B. A codon
- C. An anticodon
- D. tRNA
Correct answer: B
Rationale: The correct answer is B - A codon. A codon is a sequence of three RNA nucleotides that specifies a particular amino acid or a stop signal during protein synthesis. Choice A, a stop codon, is a sequence of three nucleotides that signals the termination of protein synthesis. Choice C, an anticodon, is a group of three nucleotides found in tRNA that pairs with the complementary codon in mRNA. Choice D, tRNA, stands for transfer RNA, which is a type of RNA that carries amino acids to the ribosome during protein synthesis.
3. Which of the following molecules contains the code required for replication?
- A. Deoxyribonucleic acid (DNA)
- B. Transfer RNA (tRNA)
- C. Messenger RNA (mRNA)
- D. Ribonucleic acid (RNA)
Correct answer: A
Rationale: The correct answer is A: Deoxyribonucleic acid (DNA). DNA contains the genetic information essential for replication, ensuring the accurate transmission of genetic material from one generation to the next. Choice B, Transfer RNA (tRNA), is involved in protein synthesis, not replication. Choice C, Messenger RNA (mRNA), carries genetic information from DNA to the ribosome but does not contain the code for replication. Choice D, Ribonucleic acid (RNA), is a broader category that includes both mRNA and tRNA, but the specific molecule containing the code required for replication is DNA.
4. The bilayer of the cellular membrane consists of phospholipids with all except which of the following scattered throughout?
- A. Nucleic acids
- B. Cholesterol
- C. Proteins
- D. Glycoproteins
Correct answer: A
Rationale: The cellular membrane is composed of a phospholipid bilayer with cholesterol, proteins, and glycoproteins distributed throughout. Nucleic acids are not found within the cellular membrane. Cholesterol helps maintain membrane fluidity, while proteins and glycoproteins play important roles in cell signaling, transport, and structural support.
5. Which of the following is often referred to as the powerhouse of the cell?
- A. Nucleus
- B. Chromatin
- C. Mitochondria
- D. Ribosomes
Correct answer: C
Rationale: Mitochondria are known as the powerhouse of the cell because they generate most of the cell's supply of ATP, which is the energy currency used for various cellular processes. The nucleus (Choice A) is the control center of the cell, housing genetic material. Chromatin (Choice B) is a complex of DNA and proteins within the nucleus. Ribosomes (Choice D) are responsible for protein synthesis and not the primary energy production in the cell.
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