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1. Which of the following is a key symptom of hyperthyroidism?
- A. Weight loss.
- B. Weight gain.
- C. Tachycardia.
- D. Dry skin.
Correct answer: A
Rationale: The correct answer is weight loss. In hyperthyroidism, there is an excess production of thyroid hormones leading to an increased metabolic rate. This increased metabolism can result in weight loss despite normal or increased appetite. Choice B (Weight gain) is more commonly associated with hypothyroidism where the metabolic rate is decreased. Choice C (Tachycardia) is another common symptom of hyperthyroidism due to the effects of thyroid hormones on the heart, causing an increased heart rate. Choice D (Dry skin) is not a typical symptom of hyperthyroidism; instead, it is more commonly associated with hypothyroidism.
2. A healthcare professional is reviewing laboratory results for a client who is at risk for nephrotoxicity due to medications. Which of the following serum creatinine results does the healthcare professional document as normal?
- A. 0.2 mg/dL
- B. 1.0 mg/dL
- C. 2.8 mg/dL
- D. 3.9 mg/dL
Correct answer: B
Rationale: The normal serum creatinine level typically ranges from 0.6 to 1.3 mg/dL. A result of 1.0 mg/dL falls within this normal range. A serum creatinine level of 0.2 mg/dL is abnormally low and may indicate decreased muscle mass or malnutrition. On the other hand, results of 2.8 mg/dL and 3.9 mg/dL are elevated, signifying impaired kidney function and potential nephrotoxicity from medications.
3. The client with type 1 diabetes mellitus is taught to take isophane insulin suspension NPH (Humulin N) at 5 PM each day. The client should be instructed that the greatest risk of hypoglycemia will occur at about what time?
- A. 11 AM, shortly before lunch.
- B. 1 PM, shortly after lunch.
- C. 6 PM, shortly after dinner.
- D. 1 AM, while sleeping.
Correct answer: D
Rationale: The correct answer is D, 1 AM, while sleeping. Isophane insulin suspension NPH (Humulin N) peaks around 6-8 hours after administration, which increases the risk of hypoglycemia during the night. Choice A, 11 AM, shortly before lunch, is incorrect because the peak effect of NPH insulin occurs much later. Choice B, 1 PM, shortly after lunch, is incorrect as it is too early for the peak effect of NPH insulin. Choice C, 6 PM, shortly after dinner, is also incorrect because the peak risk of hypoglycemia with NPH insulin occurs later in the night.
4. The healthcare professional is reviewing a patient’s chart prior to administering gentamicin (Garamycin) and notes that the last serum peak drug level was 9 mcg/mL and the last trough level was 2 mcg/mL. What action will the healthcare professional take?
- A. Administer the next dose as prescribed.
- B. Obtain repeat peak and trough levels before administering the next dose.
- C. Report potential drug toxicity to the patient’s healthcare provider.
- D. Notify the patient’s healthcare provider of decreased drug therapeutic level.
Correct answer: C
Rationale: Gentamicin peak levels should ideally be between 5 to 8 mcg/mL, and trough levels should be within the range of 0.5 to 2 mcg/mL to ensure therapeutic efficacy while minimizing toxicity risk. In this case, the patient's peak level is above the recommended range, and the trough level is at the higher end, indicating potential drug toxicity. Therefore, the correct action for the healthcare professional is to report the possibility of drug toxicity to the patient’s healthcare provider. Administering the next dose as prescribed (Choice A) would exacerbate the toxicity risk. Obtaining repeat peak and trough levels (Choice B) may confirm the current levels but does not address the immediate concern of potential toxicity. Reporting a decreased drug therapeutic level (Choice D) is not the priority in this scenario, as the focus should be on addressing the potential toxicity issue.
5. What is the primary purpose of administering IV fluids to a patient in septic shock?
- A. To reduce blood pressure.
- B. To increase cardiac output.
- C. To stabilize blood glucose levels.
- D. To maintain adequate tissue perfusion.
Correct answer: D
Rationale: The primary purpose of administering IV fluids to a patient in septic shock is to maintain adequate tissue perfusion. In septic shock, there is a significant drop in blood pressure and systemic vascular resistance leading to poor tissue perfusion. IV fluids help to restore intravascular volume, improve perfusion to vital organs, and prevent organ failure. Choice A ('To reduce blood pressure') is incorrect because IV fluids in septic shock aim to restore tissue perfusion rather than lower blood pressure. Choice B ('To increase cardiac output') is incorrect as the primary goal is to improve tissue perfusion, not specifically increase cardiac output. Choice C ('To stabilize blood glucose levels') is unrelated to the primary purpose of administering IV fluids in septic shock, which is to address the compromised tissue perfusion.
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